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Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children.

Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Research Abstract Details 

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  • Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Abstract Text:

    jouni j k jaakkolaJouni J K Jaakkola,anna a koshelevaAnna A Kosheleva,boris a katsnelsonBoris A Katsnelson,sergey v kuzminSergey V Kuzmin,larissa i privalovaLarissa I Privalova,john d spenglerJohn D Spengler,

    BACKGROUND: Only few studies have assessed the relative impact of prenatal and postnatal exposure to tobacco smoke on the child's later asthma or chronic respiratory symptoms and to our knowledge no studies have elaborated respiratory infections and allergies in this context. OBJECTIVE: To assess the effects of prenatal and postnatal exposure to tobacco smoke on respiratory health of Russian school children. METHODS: We studied a population of 5951 children (8 to 12 years old) from 9 Russian cities, whose parents answered a questionnaire on their children's respiratory health, home environment, and housing characteristics. The main health outcomes were asthma, allergies, chronic respiratory symptoms, chronic bronchitis, and upper respiratory infections. We used adjusted odds ratios (ORs) from logistic regression analyses as measures of effect. RESULTS: Prenatal exposure due to maternal smoking had the strongest effects on asthma (adjusted OR 2.46, 95% CI 1.19-5.08), chronic bronchitis (adjusted OR 1.45, 95% CI 1.08-1.96) and respiratory symptoms, such as wheezing (adjusted OR 1.30, 95% CI 0.90-1.89). The associations were weaker for exposure during early-life (adjusted ORs 1.38/1.27/1.15 respectively) and after 2 years of age (adjusted ORs 1.45/1.34/1.18) compared to prenatal exposure and the weakest or non-existent for current exposure (adjusted ORs 1.05/1.09/1.06). Upper respiratory infections were associated more strongly with early-life exposure (adjusted OR 1.25, 95% CI 1.09-1.42) than with prenatal (adjusted OR 0.74, 95% CI 0.54-1.01) or current exposure (adjusted OR1.05, 95% CI 0.92-1.20). The risk of allergies was also related to early life exposure to tobacco smoke (adjusted OR 1.26, 95% CI 1.13-1.42). CONCLUSION: Adverse effects of tobacco smoke on asthma, chronic bronchitis, and chronic respiratory symptoms are strongest when smoking takes place during pregnancy. The relations are weaker for exposure during early-life and after 2 years of age and weakest or non-existent for current exposure.

    Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Publishing Authors By Initials

    jj jaakkolaJJ Jaakkola,aa koshelevaAA Kosheleva,ba katsnelsonBA Katsnelson,sv kuzminSV Kuzmin,li privalovaLI Privalova,jd spenglerJD Spengler,

    For similar complex mixtures: particulate matter: smoke: tobacco smoke pollution research abstracts see: complex mixtures: particulate matter: smoke: tobacco smoke pollution research

    PUBMED ID PMID:

    MEDLINE DATE:

    Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Respiratory research

    VOLUME: 7

    Page Numbers: 48

    Journal Abbreviation: Respir. Res.

    ISSN: 1465-993X

    DAY: 28

    MONTH: 03

    YEAR: 2006

    Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101090633

    Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Keywords Mesh Terms:

    KEYWORDS: Tobacco Smoke Pollution

    MESH TERMS: adverse effects

    Chemical & Substance for Abstract: Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children. Information

    Substance Name: Tobacco Smoke Pollution

    Registry Number: 0

    Grant and Affiliation Information for Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children.

    AFFILIATION: Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, UK. j.jaakkola@bham.ac.uk

    Country: England

    England Research PublicationEngland Research Publication

    AGENCY: United States NIEHS

    GRANT: ES000002

    ACRONYM: ES

    MEDLINETA: Respir Res

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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