Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases.

Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Research Abstract Details 

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Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Abstract Text:

Kathleen A Meeske,Marvin D Nelson,Robert S Lavey,Sarah Gee,Mary B Nelson,Leslie Bernstein,Fred Weaver,Stuart Siegel,

BACKGROUND: Follow-up studies find an increase in stroke and carotid artery disease incidence in adult cancer patients treated with neck irradiation. These radiation-related late effects are now being detected in young adult survivors of childhood cancer. OBSERVATIONS: This report includes 5 pediatric cancer survivors, ages 23 to 40, who presented with advanced carotid artery stenosis 17 to 36 years after receiving neck irradiation. Radiation doses ranged from 3900 to 7350 cGy. Three of the 5 experienced a stroke. CONCLUSIONS: Prevalence and risk factors associated with premature carotid artery disease after neck irradiation need to be investigated in childhood cancer survivors.

Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Publishing Authors By Initials

KA Meeske,MD Nelson,RS Lavey,S Gee,MB Nelson,L Bernstein,F Weaver,S Siegel,

For similar persons: patients: survivors research abstracts see: persons: patients: survivors research

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Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of pediatric hematology/oncology : officia

VOLUME: 29

Page Numbers: 480-4

Journal Abbreviation: J. Pediatr. Hematol. Oncol.

ISSN: 1077-4114

DAY: 3

MONTH: Jul

YEAR: 2007

Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Information

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LANGUAGE: eng

NlmUniqueID: 9505928

Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases. Keywords Mesh Terms:

KEYWORDS: Survivors

MESH TERMS: adverse effects

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Grant and Affiliation Information for Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases.

AFFILIATION: Department of Pediatrics, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA. kmeeske@chla.usc.edu

Country: United States

AGENCY: United States NCI

GRANT: R03-CA-119755

ACRONYM: CA

MEDLINETA: J Pediatr Hematol Oncol

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