Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin.

Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Research Abstract Details 

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Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Abstract Text:

Y Tanaka,Y Tsunogae,Y Hayakawa,I Tanaka,T Yamane,T Ashida,C Ishikawa,K Watanabe,S Nakamura,K Takahashi,

Preliminary crystallographic studies of a Bowman-Birk type protease inhibitor, AB-I, from adzuki beans (Phaseolus angularis) 'Takara,' and its complex with trypsin were carried out. AB-I, MW 9100 with 82 amino acid residues, crystallizes in a trigonal space group, P3121 (or P3221), with the following unit cell dimensions: a = 68.7, c = 99.7 A. The asymmetric unit contains two dimer molecules. Structure analysis at 5 A resolution revealed the rough appearance of the dimer. The complex between AB-I and trypsin also could be crystallized in a tetragonal space group, P41212 (or P43212), with the unit cell dimensions, a = 55.4 and c = 181.5 A, and Z = 8. The crystallinity seems to be much better than that of the crystals of the inhibitor alone. The other type of inhibitor from adzuki bean, AB-IIa, was also crystallized.

Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Publishing Authors By Initials

Y Tanaka,Y Tsunogae,Y Hayakawa,I Tanaka,T Yamane,T Ashida,C Ishikawa,K Watanabe,S Nakamura,K Takahashi,

For similar chemical actions and uses: pharmacologic actions: molecular mechanisms of pharmacological action: enzyme inhibitors: protease inhibitors: serine proteinase inhibitors: trypsin inhibitors research abstracts see: chemical actions and uses: pharmacologic actions: molecular mechanisms of pharmacological action: enzyme inhibitors: protease inhibitors: serine proteinase inhibitors: trypsin inhibitors research

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Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 94

Page Numbers: 611-3

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Aug

YEAR: 1983

Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Keywords Mesh Terms:

KEYWORDS: Trypsin Inhibitors

MESH TERMS: analysis

Chemical & Substance for Abstract: Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin. Information

Substance Name: Trypsin

Registry Number: EC 3.4.21.4

Grant and Affiliation Information for Preliminary crystallographic study of Bowman-Birk protease inhibitor (adzuki bean) and its complex with trypsin.

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Country: JAPAN

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MEDLINETA: J Biochem

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