Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience.

Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience. Research Abstract Details 

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Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience. Abstract Text:

K W Joo,S J Shin,S H Lee,J W Ha,S Kim,Y S Kim,K W Joo,S J Shin,S H Lee,J W Ha,S Kim,Y S Kim,K W Joo,S J Shin,S H Lee,J W Ha,S Kim,Y S Kim,

Although preemptive transplantation of kidneys from living donors without the previous initiation of dialysis is associated with longer allograft survival in a USRDS cohort, the effect of pretransplantation dialysis on graft outcome is still controversial in Korea. The purpose of this study was to evaluate the differential effects on long-term outcomes of living donor kidney transplantation according to initiation of dialysis and its duration or no dialysis. We performed a retrospective cohort study of 494 patients who received a first kidney transplant from a living donor between 1990 and 2006. The mean duration for dialysis was 14.5 +/- 22.2 months. The 10-year patient survival of 98.0% in the preemptive group was not significantly higher than the dialysis group (91.2%, P > .05). However, 10-year graft survival was higher in the preemptive than the dialysis group (preemptive 94.4%, dialysis 76.5%; P < .05). The differential effect of pretransplant dialysis either by hemodialysis or peritoneal dialysis was not significant, although peritoneal dialysis as a pretransplant treatment seemed to be beneficial on long-term graft survival (5-year graft survival; peritoneal 94.8% and hemodialysis 89.2%). The duration of dialysis did not affect graft survival in our study cohort. In conclusion, we suggest that preemptive transplantation should be applied to eligible patients.

Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience. Publishing Authors By Initials

KW Joo,SJ Shin,SH Lee,JW Ha,S Kim,YS Kim,KW Joo,SJ Shin,SH Lee,JW Ha,S Kim,YS Kim,KW Joo,SJ Shin,SH Lee,JW Ha,S Kim,YS Kim,

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Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Transplantation proceedings

VOLUME: 39

Page Numbers: 3061-4

Journal Abbreviation: Transplant. Proc.

ISSN: 0041-1345

DAY: 19

MONTH: Dec

YEAR: 2007

Preemptive transplantation and long-term outcome in living donor kidney transplantation, single-center experience. Information

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LANGUAGE: eng

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AFFILIATION: Seoul National University College of Medicine, Seoul, South Korea.

Country: United States

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MEDLINETA: Transplant Proc

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