Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients.

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Abstract Text:

Hiromitsu Hayashi,Toru Beppu,Toshiro Masuda,Takao Mizumoto,Masashi Takahashi,Takatoshi Ishiko,Hiroshi Takamori,Keiichiro Kanemitsu,Masahiko Hirota,Hideo Baba,Hiromitsu Hayashi,Toru Beppu,Toshiro Masuda,Takao Mizumoto,Masashi Takahashi,Takatoshi Ishiko,Hiroshi Takamori,Keiichiro Kanemitsu,Masahiko Hirota,Hideo Baba,

BACKGROUND AND AIM: Partial splenic embolization (PSE) is often performed for improving thrombocytopenia in cirrhotic patients. We investigated the largely unclear predictive factors for platelet increase at both 1 month and 1 year after PSE. METHODS: Aimed at increasing the platelet count, PSE was performed in 42 cirrhotic patients with thrombocytopenia (platelets < 80 x 10(4)/mL) caused by hypersplenism. The clinical data were analyzed to clarify the predictive factors for platelet increase at 1 month (n = 42) and 1 year (n = 38) after PSE. RESULTS: The mean splenic infarction ratio was 76.7% +/- 11.2%. The platelet count increased to 259% +/- 112% and 228% +/- 75% of the pretreatment values at 1 month and at 1 year after PSE, respectively. Stepwise multiple linear regression analysis showed that the infarcted splenic volume had a positive independent association with the increase in platelet count at both 1 month (P = 0.00004) and 1 year (P = 0.005) after PSE (increase in platelet count (x10(4)/mL): at 1 month = 0.752 + 0.018 x infarcted splenic volume (mL), R(2) = 0.344; at 1 year = 2.19 + 0.01 x infarcted splenic volume (mL), R(2) = 0.203). Receiver operating characteristic analysis yielded a cut-off value of 388 mL of infarcted splenic volume for achieving an increase of 5.0-8.0 x 10(4)/mL in platelet count at 1 year. CONCLUSIONS: PSE can reduce the platelet pool and induce an increase in platelet count. This increase is greatly dependent on the infarcted splenic volume.

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Publishing Authors By Initials

H Hayashi,T Beppu,T Masuda,T Mizumoto,M Takahashi,T Ishiko,H Takamori,K Kanemitsu,M Hirota,H Baba,H Hayashi,T Beppu,T Masuda,T Mizumoto,M Takahashi,T Ishiko,H Takamori,K Kanemitsu,M Hirota,H Baba,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of gastroenterology and hepatology

VOLUME: 22

Page Numbers: 1638-42

Journal Abbreviation: J. Gastroenterol. Hepatol.

ISSN: 0815-9319

DAY: 7

MONTH: 08

YEAR: 2007

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8607909

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients.

AFFILIATION: Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Country: Australia

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Gastroenterol Hepatol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients Related Publications

• Charging dynamics of the electric double layer in porous media.
• Cloning and functional expression of cycloartenol synthases from mangrove species Rhizophora stylosa Griff. and Kandelia candel (L.) Druce.
• Comparison of intrahepatic and pancreatic perfusion on fusion images using a combined SPECT/CT system and assessment of efficacy of combined continuous arterial infusion and systemic chemotherapy in advanced pancreatic carcinoma.
• Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) blocks the chemotaxis of neutrophils by inhibiting signal transduction through IL-8 receptors.
• Detection of a mixed infection of a novel Cryptosporidium andersoni and its subgenotype in Japanese cattle.
• Dipole-LUMO/dipolarophile-HOMO controlled asymmetric cycloadditions of carbonyl ylides catalyzed by chiral Lewis acids.
• Effects of Salmonella enterica subsp. enterica serovar Enteritidis vaccination in layer hens subjected to S. Enteritidis challenge and various feed withdrawal regimens.
• Efficacy of etanercept in patients with AA amyloidosis secondary to rheumatoid arthritis.
• Embryogenesis and swimming behavior of Medaka fish in JUSTSAP STARS Program (STS-107).
• Experiences in quality assurance at Bawku Hospital Eye Department, Ghana.
• Gemcitabine and paclitaxel chemotherapy as a second-line treatment for advanced or metastatic urothelial carcinoma.
• InCl3/I2-catalyzed cross-coupling of alkyl trimethylsilyl ethers and allylsilanes via an in situ derived combined Lewis acid of InCl3 and Me3SiI.
• Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor.
• Low-group-velocity and low-dispersion slow light in photonic crystal waveguides.
• Ossification of the posterior longitudinal ligament of the cervical spine: histopathological findings around the calcification and ossification front.
• Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia.
• Posterior 360-degree stabilisation of the upper thoracic spine: a technical note.
• Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101.
• Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patients.
• Prognostic relevance of activated Akt kinase in node-negative breast cancer: a clinicopathological study of 99 cases.
• Quantitative gait analysis of patients with bilateral hip osteoarthritis excluding the influence of walking speed.
• Sensory aphasia after closed head injury.
• Single-molecule measurements with a single quantum dot.
• The red eye - first aid at the primary level.
• Thoracic ossification of the human ligamentum flavum: histopathological and immunohistochemical findings around the ossified lesion.
• X-ray absorption beamline at the Mitsubishi compact storage ring.
• [Circadian rhythm monitoring in an individual animal]
• [High-normal blood pressure]
• [Molecular pharmacologic approaches to functional analysis of new biological target molecules for drug discovery]
• [Studies on chemical constituents from roots of Peucedanum praeruptorum II]