Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis.

Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Research Abstract Details 

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Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Abstract Text:

S Ioffe,V Chernick,S Ioffe,V Chernick,

In a prospective, blinded study 38 infants of mothers with varying quantities of alcohol ingestion during pregnancy had an EEG at 40 weeks post conceptional age. Bayley Development Tests were administered between 1.5 and 10 months of age. The total power of the EEG during REM sleep was inversely related to subsequent motor development (r = -0.51, F = 13.1, p less than 0.0008) whereas the total power of the EEG during quiet sleep was inversely related to subsequent mental development (r = 0.61, F = 24.4, p less than 0.0001). In alcohol exposed babies EEG abnormalities were present even in the absence of fetal alcohol syndrome (FAS). In 16 older children born to abstainers or alcoholic mothers similar results were obtained. Thus, the power of the EEG during REM and quiet sleep at birth appears to be a sensitive index of alcohol effects on the fetal brain and may be used to predict future motor and mental development.

Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Publishing Authors By Initials

S Ioffe,V Chernick,S Ioffe,V Chernick,

For similar sleep research abstracts see: sleep research

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Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Neuropediatrics

VOLUME: 21

Page Numbers: 11-7

Journal Abbreviation: Neuropediatrics

ISSN: 0174-304X

DAY: 16

MONTH: Feb

YEAR: 1990

Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Information

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LANGUAGE: eng

NlmUniqueID: 8101187

Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Keywords Mesh Terms:

KEYWORDS: Sleep

MESH TERMS: drug effects

Chemical & Substance for Abstract: Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis. Information

Substance Name: Ethanol

Registry Number: 64-17-5

Grant and Affiliation Information for Prediction of subsequent motor and mental retardation in newborn infants exposed to alcohol in utero by computerized EEG analysis.

AFFILIATION: Department of Pediatrics, University of Manitoba, Winnipeg, Canada.

Country: GERMANY, WEST

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MEDLINETA: Neuropediatrics

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