It has been reported earlier [Hopp, T.P. & Woods, K.R. (1981) Proc. Natl. Acad. Sci. US 78, 3824-3828] that the antigenic determinants of a protein can be delineated by examining the average local hydrophilicity values along the peptide chain. I have used this method to predict the strong antigenic determinants of two proteins, seminalplasmin and ribonuclease, of known sequence. In the former case, the N-terminal segment 1-14, and in the latter case the segments 27-38 and 80-86, are predicted to possess the antigenic determinants of the two proteins. Experimental verification already exists for the former case.
Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence. Publishing Authors By Initials
Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: International journal of peptide and protein resea
VOLUME: 25
Page Numbers: 197-9
Journal Abbreviation: Int. J. Pept. Protein Res.
ISSN: 0367-8377
DAY: 19
MONTH: Feb
YEAR: 1985
Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 330420
Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence. Keywords Mesh Terms:
KEYWORDS: Seminal Vesicle Secretory Proteins
MESH TERMS: immunology
Chemical & Substance for Abstract: Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence. Information
Substance Name: Ribonuclease, Pancreatic
Registry Number: EC 3.1.27.5
Grant and Affiliation Information for Prediction of strong antigenic determinant of seminalplasmin and ribonuclease from the amino acid sequence.
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Country: DENMARK
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MEDLINETA: Int J Pept Protein Res
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