Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies.

Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies. Research Abstract Details 

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Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies. Abstract Text:

Kazuo Awai,Yoshiharu Nakayama,Takeshi Nakaura,Yumi Yanaga,Yoshitaka Tamura,Masahiro Hatemura,Yoshinori Funama,Yasuyuki Yamashita,Kazuo Awai,Yoshiharu Nakayama,Takeshi Nakaura,Yumi Yanaga,Yoshitaka Tamura,Masahiro Hatemura,Yoshinori Funama,Yasuyuki Yamashita,

PURPOSE: The aim of this study was to investigate whether it is possible to predict aortic peak enhancement (APE) from the contrast dose and injection rate. MATERIALS AND METHODS: We first undertook an experimental study using a flow phantom that simulates the human circulation. We delivered 90-150 ml of iomeprol-350 at various injection rates and measured the APE values of the simulated aorta. In our clinical study we randomized 20 patients into four groups. In groups A, B, and C the iodine dose per kilogram of body weight (BW) ranged from 450 to 600 mg, and the injection duration was fixed at 30 s; group D received 450 mg/kg over 25 s. We then measured APE in all patients at the whole aorta, averaged the three highest values, and took the result as APE. RESULTS: In the phantom study, the decision coefficient for the best-fit equation obtained by multiple regression analysis of the relation between the iodine dose and injection rate and the simulated APE was high (0.93). In the patient study, the predicted APE values almost corresponded with the averaged APE values when we applied the fitness equation. CONCLUSION: Using our fitness equation, APE on contrast-enhanced computed tomography can be predicted from the iodine dose and the contrast injection rate per patient weight.

Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies. Publishing Authors By Initials

K Awai,Y Nakayama,T Nakaura,Y Yanaga,Y Tamura,M Hatemura,Y Funama,Y Yamashita,K Awai,Y Nakayama,T Nakaura,Y Yanaga,Y Tamura,M Hatemura,Y Funama,Y Yamashita,

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Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies. Journal Published:

PUBLICATION TYPE: Randomized Controlled Trial

Journal: Radiation medicine

VOLUME: 25

Page Numbers: 14-21

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ISSN: 0288-2043

DAY: 25

MONTH: 01

YEAR: 2007

Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies.

AFFILIATION: Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan. awai@kaiju.medic.kumamoto-u.ac.jp

Country: Japan

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MEDLINETA: Radiat Med

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