Preclinical models for chemoprevention of colon cancer.

Preclinical models for chemoprevention of colon cancer. Research Abstract Details 

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Preclinical models for chemoprevention of colon cancer. Abstract Text:

Eugene W Gerner,Natalia A Ignatenko,David G Besselsen,

Colon cancer is the second leading cause of cancer incidence and death in the USA in 2002. Specific genetic defects have been identified which cause hereditary colon cancers in humans. In addition, a number of intestinal luminal risk factors for colon cancer have been described. This information has been exploited to develop experimental cell and rodent models which recapitulate features of human colon cancer. In this chapter, we will discuss the strengths and limitations of these models to further our understanding of basic mechanisms of colon carcinogenesis and to develop strategies for colon cancer chemoprevention.

Preclinical models for chemoprevention of colon cancer. Publishing Authors By Initials

EW Gerner,NA Ignatenko,DG Besselsen,

For similar animal diseases: disease models, animal research abstracts see: animal diseases: disease models, animal research

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Preclinical models for chemoprevention of colon cancer. Journal Published:

PUBLICATION TYPE: Review

Journal: Recent results in cancer research. Fortschritte de

VOLUME: 163

Page Numbers: 58-71; discussion 264-6

Journal Abbreviation: Recent Results Cancer Res.

ISSN: 0080-0015

DAY: 13

MONTH: 02

YEAR: 2003

Preclinical models for chemoprevention of colon cancer. Information

Number of References: 74

LANGUAGE: eng

NlmUniqueID: 44671

Preclinical models for chemoprevention of colon cancer. Keywords Mesh Terms:

KEYWORDS: Disease Models, Animal

MESH TERMS: prevention & control

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Grant and Affiliation Information for Preclinical models for chemoprevention of colon cancer.

AFFILIATION: Arizona Radiation Oncology, The University of Arizona, 1515 N Campbell, P.O. Box 240524, Tucson, AZ 85724, USA.

Country: Germany

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MEDLINETA: Recent Results Cancer Res

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