Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma.

Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Research Abstract Details 

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Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Abstract Text:

S Sumi,Y Yamashita,K Mitsuzaki,H Yamamoto,J Urata,T Nishiharu,M Takahashi,

OBJECTIVE: This study was undertaken to determine the value of power Doppler sonography in the evaluation of recurrent hepatocellular carcinomas after transcatheter arterial chemoembolization therapy. SUBJECTS AND METHODS: Forty-five patients (age range, 45-81 years; mean age, 61 years) with hepatocellular carcinomas prospectively underwent power Doppler sonography, helical CT, and intraarterial digital subtraction angiography before and after transcatheter arterial chemoembolization therapy to evaluate for tumor recurrence. Three to 6 months after transcatheter arterial chemoembolization therapy, the Doppler signal, its location, and shape were evaluated. The results were compared with tumor vascularity as determined on helical CT and intraarterial digital subtraction angiography, which were used as the gold standards (n = 142). RESULTS: A sonographic signal was seen in 80 of 142 lesions with power Doppler sonography. Flow signal in lesions tended to be more difficult to detect in the left lobe (sensitivity, 74%) than in the right lobe (sensitivity, 93%). The location of the color signal was in the tumor's center, on its periphery, or both. No correlation between tumor recurrence and the location of a signal within a tumor was found. Power Doppler sonography had a sensitivity of 87%, a specificity of 85%, and an accuracy of 86% in revealing tumor recurrence after transcatheter arterial chemoembolization therapy. All lesions that showed linear signals in the center or at the periphery of the tumors proved to be recurring tumors (n = 20). In lesions with spotty signals, tumor recurrence was not revealed in nine of 60 lesions. CONCLUSION: Power Doppler sonography can be used for follow-up studies after transcatheter arterial chemoembolization therapy as a sensitive and cost-effective imaging technique. Although spotty signals were frequently seen, linear signals appeared to be specific for tumor recurrence.

Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Publishing Authors By Initials

S Sumi,Y Yamashita,K Mitsuzaki,H Yamamoto,J Urata,T Nishiharu,M Takahashi,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, doppler research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, doppler research

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Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 172

Page Numbers: 67-71

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ISSN: 0361-803X

DAY: 15

MONTH: Jan

YEAR: 1999

Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma. Keywords Mesh Terms:

KEYWORDS: Ultrasonography, Doppler

MESH TERMS: ultrasonography

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Grant and Affiliation Information for Power Doppler sonography assessment of tumor recurrence after chemoembolization therapy for hepatocellular carcinoma.

AFFILIATION: Department of Radiology, Kumamoto University School of Medicine, Japan.

Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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