Potential cardiotoxicity with the use of DuP-941: a case report.

Potential cardiotoxicity with the use of DuP-941: a case report. Research Abstract Details 

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Potential cardiotoxicity with the use of DuP-941: a case report. Abstract Text:

S M Walsh,V M Walley,L Chandra,S D Huan,J P Veinot,L A Higginson,

OBJECTIVE: To describe the clinical and pathological features of a patient with probable cardiotoxicity related to a newer chemotherapeutic agent, DuP-941. PATIENT AND METHODS: A 42-year-old woman with metastatic breast carcinoma treated with only DuP-941 developed, and died of, heart failure for which no other explanation was apparent. RESULTS: Clinically the patient's heart failure resembled that associated with anthracycline cardiotoxicity, as did the pathological features seen at autopsy. CONCLUSION: DuP-941 is a new chemotherapeutic drug that may supplant some uses of the anthracyclines because the former may have less cardiotoxicity. This report suggests that in some cases DuP-941 may have cardiotoxic effects as well.

Potential cardiotoxicity with the use of DuP-941: a case report. Publishing Authors By Initials

SM Walsh,VM Walley,L Chandra,SD Huan,JP Veinot,LA Higginson,

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: azoles: pyrazoles: pyrazolones research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: azoles: pyrazoles: pyrazolones research

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Potential cardiotoxicity with the use of DuP-941: a case report. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Canadian journal of cardiology

VOLUME: 11

Page Numbers: 419-22

Journal Abbreviation:

ISSN: 1916-7075

DAY: 3

MONTH: May

YEAR: 1995

Potential cardiotoxicity with the use of DuP-941: a case report. Information

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LANGUAGE: eng

NlmUniqueID: 8510280

Potential cardiotoxicity with the use of DuP-941: a case report. Keywords Mesh Terms:

KEYWORDS: Pyrazolones

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Potential cardiotoxicity with the use of DuP-941: a case report. Information

Substance Name: losoxantrone

Registry Number: 88303-60-0

Grant and Affiliation Information for Potential cardiotoxicity with the use of DuP-941: a case report.

AFFILIATION: Department of Medicine, University of Ottawa Heart Institute, Ottawa Civic Hospital, Ontario.

Country: CANADA

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MEDLINETA: Can J Cardiol

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