Post-traumatic fungal endophthalmitis-a prospective study.

Post-traumatic fungal endophthalmitis-a prospective study. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Post-traumatic fungal endophthalmitis-a prospective study. Abstract Text:

A Gupta,R Srinivasan,S Kaliaperumal,I Saha,A Gupta,R Srinivasan,S Kaliaperumal,I Saha,

PurposeTo study the incidence, clinical presentation, and the response of anti-fungals in cases of fungal endophthalmitis following open globe injury.MethodsThis is a prospective study of eight cases of post-traumatic fungal endophthalmitis among 110 patients who presented to us with open globe injury between August 2003 and January 2005. Patients with panophthalmitis were eviscerated and rest received intravitreal amphotericin B. Pars plana vitrectomy along with intravitreal miconazole was given in patients with inadequate response to intravitreal amphotericin.ResultsTwo patients had panophthalmitis at the time of presentation and were eviscerated. Six different organisms were isolated from the culture of intraocular specimen of eight patients. The yield of vitreous aspirate was 87.5% and that of aqueous aspirate was 66.6%. Aspergillussp. and Fusariumsp. were isolated in 62.5% of cases. Minimum inhibitory concentration of amphotericin B and miconazole was less than 3 mug/ml for all organisms except for Paecilomyces lilacinusand Fusarium solani, respectively. In total, 37.5% of patient had final visual acuity of 20/400 or better.ConclusionsFungal endophthalmitis is a relatively rare complication of open globe injury. The final visual outcome after fungal endophthalmitis is dismal. Aspergillus fumigatuswas found to be the most virulent organism. All organisms were found to be sensitive to amphotericin B, except P. lilacinus, which was sensitive to miconazole. Repeated intravitreal injection may be required to control the infection. The virulence of the organism and the site of injury are the main determinants of final visual outcome.Eye (2008) 22, 13-17; doi:10.1038/sj.eye.6702463; published online 2 June 2006.

Post-traumatic fungal endophthalmitis-a prospective study. Publishing Authors By Initials

A Gupta,R Srinivasan,S Kaliaperumal,I Saha,A Gupta,R Srinivasan,S Kaliaperumal,I Saha,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Post-traumatic fungal endophthalmitis-a prospective study. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Eye (London, England)

VOLUME: 22

Page Numbers: 13-7

Journal Abbreviation:

ISSN: 0950-222X

DAY: 2

MONTH: 06

YEAR: 2006

Post-traumatic fungal endophthalmitis-a prospective study. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8703986

Post-traumatic fungal endophthalmitis-a prospective study. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Post-traumatic fungal endophthalmitis-a prospective study. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Post-traumatic fungal endophthalmitis-a prospective study.

AFFILIATION: 1Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Eye

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Post-traumatic fungal endophthalmitis-a prospective study Related Publications

• A brief guide to clinical guidelines.
• A gamma camera re-evaluation of potassium iodide blocking efficiency in mice.
• A novel functional approach toward identifying definitive drug targets.
• CD40-induced countercurrent conduits for tumor escape or elimination?
• Coexistent partial anodontia and supernumerary tooth in the mandibular arch: A rare case.
• Communicative competence: a framework for understanding language barriers in health care.
• Comparative bioavailability of metoprolol tartrate after oral and transdermal administration in healthy male volunteers.
• Comparative evaluation of ophthalmoscopy and angiography for the assessment of retinopathy in type 2 diabetes mellitus.
• Comparison of calcium phosphate product values using measurement of plasma total calcium and serum ionized calcium.
• Comparison of health and effective functioning in Russia and the United States.
• Computer-assisted lateralization of unilateral temporal lobe epilepsy using Z-score parametric F-18 FDG PET images.
• Criticality in inhomogeneous magnetic systems: application to quantum ferromagnets.
• Current status and future clinical applications of lymphatic mapping in gastrointestinal cancer.
• Design and study of lamivudine oral controlled release tablets.
• Dialysis dose and the diagnosis of hypertension in hemodialysis patients.
• Disability in Indian patients with haemophilia.
• Functional paradox in host-pathogen interaction dictates the fate of parasites.
• Genistein from Flemingia vestita (Fabaceae) enhances NO and its mediator (cGMP) production in a cestode parasite, Raillietina echinobothrida.
• Glancing incidence EUV telescopes: analysis and comparison.
• Growth kinetics of an indigenous mixed microbial consortium during phenol degradation in a batch reactor.
• Hexagonal packing of cis,cis-cyclohexane-1,3,5-tricarboxamide.
• Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A.
• Pharmacophore mapping of arylbenzothiophene derivatives for MCF cell inhibition using classical and 3D space modeling approaches.
• Population transfer to excited vibrational levels of H2 molecule by stimulated hyper-Raman passage with chirped laser pulses.
• Post-traumatic fungal endophthalmitis-a prospective study.
• Predatory efficiency of the sewage drain inhabiting larvae of Toxorhynchites splendens Wiedemann on Culex quinquefasciatus Say and Armigeres subalbatus (Coquillett) larvae.
• Safety and effect of chlorhexidine skin cleansing on skin flora of neonates in Bangladesh.
• Sustained Metaphase Arrest in Response to Ionizing Radiation in a Non-small Cell Lung Cancer Cell Line.
• [In Process Citation]
• mRNA cycling sequence binding protein from Leishmania donovani (LdCSBP) is covalently modified by ubiquitination.