[Post mortem determination of bromureides (author's transl)]

[Post mortem determination of bromureides (author's transl)] Research Abstract Details 

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[Post mortem determination of bromureides (author's transl)] Abstract Text:

H Käferstein,G Sticht,

Concentrations of carbromal, carbromide and bromisoval are determined in blood, urine, brain, kidney and muscle taken at autopsy from 41 fatal cases after overdosage of bromureides. In addition values of total bromine in blood are presented. Contents of total bromine can only lead to the deduction that a chronical abuse of bromureides is existent or not. Concentrations of bromureides and carbromide show a wide range according to the different time between taking the drug and death particularly in cases of pure carbromal intoxications which sometimes cause death after several days. In such cases quantitative determination of carbromide, a pharmacologically active metabolite of carbromal, is the only way to prove an acute carbromal intoxication. Especially in cases of additional foreign substances death may occur in early the phase of poisoning. Bromureides decompose post mortem by putrefaction a high degree so that the condition of the cadaver is important. Brain tissue is the most usable material for examination but other organs, particularly muscle and kidney, can be analysed with success. For differential diagnosis fatal cases are presented which were not caused by drug intake.

[Post mortem determination of bromureides (author's transl)] Publishing Authors By Initials

H Käferstein,G Sticht,

For similar organic chemicals: urea research abstracts see: organic chemicals: urea research

PUBMED ID PMID:

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[Post mortem determination of bromureides (author's transl)] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Rechtsmedizin. Journal of legal me

VOLUME: 81

Page Numbers: 269-83

Journal Abbreviation: Z. Rechtsmed.

ISSN: 0044-3433

DAY: 28

MONTH: Aug

YEAR: 1978

[Post mortem determination of bromureides (author's transl)] Information

Number of References:

LANGUAGE: ger

NlmUniqueID: 247437

[Post mortem determination of bromureides (author's transl)] Keywords Mesh Terms:

KEYWORDS: Urea

MESH TERMS: urine

Chemical & Substance for Abstract: [Post mortem determination of bromureides (author's transl)] Information

Substance Name: Bromine

Registry Number: 7726-95-6

Grant and Affiliation Information for [Post mortem determination of bromureides (author's transl)]

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Country: GERMANY, WEST

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MEDLINETA: Z Rechtsmed

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