[Possible role of the FGF23-Klotho axis in bone mineralization]

[Possible role of the FGF23-Klotho axis in bone mineralization] Research Abstract Details 

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[Possible role of the FGF23-Klotho axis in bone mineralization] Abstract Text:

Takashi Shimada,Takashi Shimada,

FGF23 was identified as a causative factor for hypophosphatemic rickets/osteomalacia. The following studies have confirmed its essential role in phosphate and vitamin D metabolism in normal physiology. Recent studies revealed that Klotho, originally identified as an aging-associated molecule, is necessary for the specific action of FGF23. Much attention is now paid to the FGF23-Klotho axis as a novel regulatory system in the mineral metabolism, whereas local action of FGF23 in bone metabolism or bone mineralization remains unresolved.

[Possible role of the FGF23-Klotho axis in bone mineralization] Publishing Authors By Initials

T Shimada,T Shimada,

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[Possible role of the FGF23-Klotho axis in bone mineralization] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical calcium

VOLUME: 17

Page Numbers: 1548-53

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ISSN: 0917-5857

DAY: 1

MONTH: Oct

YEAR: 2007

[Possible role of the FGF23-Klotho axis in bone mineralization] Information

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LANGUAGE: jpn

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AFFILIATION: Kirin Pharma Co., Ltd., Discovery Research Laboratories, Nephrology.

Country: Japan

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MEDLINETA: Clin Calcium

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