Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure.

Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Research Abstract Details 

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Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Abstract Text:

D Michalk,W Tschöpe,H J Böhles,O Mehls,

In order to investigate the role of hypersulphataemia in the development of hyperparathyroidism the blood levels of inorganic sulphate (SO4(2-)) and phosphate (HPO4(2-)) were compared with total and ionised calcium (Ca) and parathyroid hormone (PTH) in 20 patients with chronic renal failure (CRF). There was a positive correlation between plasma SO4(2-) and serum creatinine. Ionised Ca was inversely correlated with HPO4(2-), SO4(2-) and PTH, respectively. The best correlation was found between ionised Ca and the ion product of HPO4(2-) and SO4(2-). It is suggested that hypersulphataemia might be involved in the pathogenesis of secondary hyperparathyroidism and osteodystrophy in CRF by complex formation with Ca, thereby aggravating the effect of HPO4(2-) on ionised Ca and the resulting PTH stimulation.

Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Publishing Authors By Initials

D Michalk,W Tschöpe,HJ Böhles,O Mehls,

For similar inorganic chemicals: electrolytes: ions: anions: sulfates research abstracts see: inorganic chemicals: electrolytes: ions: anions: sulfates research

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Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Proceedings of the European Dialysis and Transplan

VOLUME: 18

Page Numbers: 561-6

Journal Abbreviation:

ISSN: 0071-2736

DAY: 21

MONTH: 02

YEAR: 1981

Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Information

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LANGUAGE: eng

NlmUniqueID: 355210

Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Keywords Mesh Terms:

KEYWORDS: Sulfates

MESH TERMS: blood

Chemical & Substance for Abstract: Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure. Information

Substance Name: Calcium

Registry Number: 7440-70-2

Grant and Affiliation Information for Possible role of inorganic sulphate in the pathogenesis of hyperparathyroidism in chronic renal failure.

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Country: ENGLAND

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MEDLINETA: Proc Eur Dial Transplant Assoc

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