Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions.

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Research Abstract Details 

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Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Abstract Text:

Violeta Chitu,E Richard Stanley,

Cellular adhesion, motility, endocytosis, exocytosis and cytokinesis involve the coordinated reorganization of the cytoskeleton and of the plasma membrane. The 'Pombe Cdc15 homology' (PCH) family of adaptor proteins has recently been shown to coordinate the membrane and cytoskeletal dynamics involved in these processes by curving membranes, recruiting dynamin and controlling the architecture of the actin cytoskeleton. Mutations in PCH family members or proteins that interact with them are associated with autoinflammatory, neurological or neoplastic diseases. Here, we review the nature, actions and disease associations of the vertebrate PCH family members, highlighting their fundamental roles in the regulation of processes involving membrane-cytoskeletal interactions.

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Publishing Authors By Initials

V Chitu,ER Stanley,

For similar biochemical phenomena, metabolism, and nutrition: metabolism: biological transport: protein transport research abstracts see: biochemical phenomena, metabolism, and nutrition: metabolism: biological transport: protein transport research

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Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Journal Published:

PUBLICATION TYPE: Review

Journal: Trends in cell biology

VOLUME: 17

Page Numbers: 145-56

Journal Abbreviation: Trends Cell Biol.

ISSN: 0962-8924

DAY: 12

MONTH: 02

YEAR: 2007

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Information

Number of References: 103

LANGUAGE: eng

NlmUniqueID: 9200566

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Keywords Mesh Terms:

KEYWORDS: Protein Transport

MESH TERMS: metabolism

Chemical & Substance for Abstract: Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Information

Substance Name: Adaptor Proteins, Signal Transducing

Registry Number: 0

Grant and Affiliation Information for Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions.

AFFILIATION: Department of Developmental Biology and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA.

Country: England

AGENCY: United States NCI

GRANT: R01S CA25604

ACRONYM: CA

MEDLINETA: Trends Cell Biol

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