Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies.

Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Research Abstract Details 

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Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Abstract Text:

M E Krautwald,H Müller,E F Kaleta,

In order to get insight into the aetiology of French Moult (FM) and Budgerigar Fledgling Disease (BFD), and to determine relationships between the two diseases, 298 budgerigars from 49 different breeding flocks were examined. From all birds with BFD and from several birds with FM, viruses were isolated which produced characteristic cytopathic changes in chicken embryo fibroblasts. They were insensitive to chloroform treatment, and their replication was inhibited in the presence of 5-iododeoxyuridine. One of these isolates, from a bird exhibiting clinical signs of BFD, was determined by biochemical and biophysical methods to be a polyomavirus (BFDV). Nestling budgerigars 3 to 10 days of age, were inoculated with this BFDV isolate. They developed an acute systemic disease with high mortality rates, similar to naturally occurring infections. In this regard, BFDV differs markedly from all the other polyomaviruses known until now which only cause clinically asymptomatic, persistent infections in their natural hosts. Most of the birds examined with clinical signs of BFD or FM exhibited low titers of antibodies neutralizing the BFDV isolate, whereas in clinically healthy birds from flocks that never had any problems with FM or BFD, no antibodies against BFDV could be detected. On account of the results of our experiments described here we suspect that FM might be a milder, more protracted form of a BFDV infection.

Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Publishing Authors By Initials

ME Krautwald,H Müller,EF Kaleta,

For similar virus diseases: tumor virus infections research abstracts see: virus diseases: tumor virus infections research

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Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 36

Page Numbers: 459-67

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: Aug

YEAR: 1989

Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Information

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LANGUAGE: eng

NlmUniqueID: 331325

Polyomavirus infection in budgerigars (Melopsittacus undulatus): clinical and aetiological studies. Keywords Mesh Terms:

KEYWORDS: Tumor Virus Infections

MESH TERMS: veterinary

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Country: GERMANY, WEST

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MEDLINETA: Zentralbl Veterinarmed B

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