Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol.

Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Research Abstract Details 

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Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Abstract Text:

Da Yang,David F O'Brien,Seth R Marder,

Bicontinuous cubic phases of monoacylglycerides/Poloxamer 407 (PEO98PPO67PEO98)/water can be dispersed into submicron particles, which are termed "cubosomes". Technological applications of these nanoparticles may be possible, if their nonlamellar architecture can be rendered more robust. To accomplish this goal, a polymerizable heterobifunctional monoacylglycerol, 3-(2,4,13-(E,E)-tetradecatrienoyl)-sn-glycerol (1), was synthesized and combined with water to form an optically transparent gel. In the presence of Poloxamer 407 and excess water the cubic phase of 1 was dispersed by ultrasonication into 300-nm diameter nanoparticles. The polymerization of these reactive cubosomes could be initiated either by the use of a photoinitiator or with redox chemistry. The polymerized cubosomes remained stable even after the addition of excess Triton X-100, in a manner consistent with executing cross-linking in the nanostructures.

Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Publishing Authors By Initials

D Yang,DF O'Brien,SR Marder,

For similar chemical actions and uses: specialty uses of chemicals: surface-active agents research abstracts see: chemical actions and uses: specialty uses of chemicals: surface-active agents research

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Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 124

Page Numbers: 13388-9

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 13

MONTH: Nov

YEAR: 2002

Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Keywords Mesh Terms:

KEYWORDS: Surface-Active Agents

MESH TERMS: chemistry

Chemical & Substance for Abstract: Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol. Information

Substance Name: Octoxynol

Registry Number: 9002-93-1

Grant and Affiliation Information for Polymerized bicontinuous cubic nanoparticles (cubosomes) from a reactive monoacylglycerol.

AFFILIATION: C. S. Marvel Laboratories, Department of Chemistry, University of Arizona, Tucson 85721, USA.

Country: United States

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MEDLINETA: J Am Chem Soc

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