Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process.

Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process. Research Abstract Details 

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Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process. Abstract Text:

Industrial ethanol fermentation is a non-sterile process and contaminant microorganisms can lead to a decrease in industrial productivity and significant economic loss. Nowadays, some distilleries in Northeastern Brazil deal with bacterial contamination by decreasing must pH and adding bactericides. Alternatively, contamination can be challenged by adding a pure batch of Saccharomyces cerevisiae-a time-consuming and costly process. A better strategy might involve the development of a fungicide that kills contaminant yeasts while preserving S. cerevisiae cells. Here, we show that polyhexamethyl biguanide (PHMB) inhibits and kills the most important contaminant yeasts detected in the distilleries of Northeastern Brazil without affecting the cell viability and fermentation capacity of S. cerevisiae. Moreover, some physiological data suggest that PHMB acts through interaction with the yeast membrane. These results support the development of a new strategy for controlling contaminant yeast population whilst keeping industrial yields high.

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Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of industrial microbiology & biotechnology

VOLUME: 35

Page Numbers: 967-73

Journal Abbreviation: J. Ind. Microbiol. Biotechnol.

ISSN: 1367-5435

DAY: 28

MONTH: 05

YEAR: 2008

Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process.

AFFILIATION: Departamento de Genética, Universidade Federal de Pernambuco, Av. Moraes Rego, 1235 Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.

Country: England

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MEDLINETA: J Ind Microbiol Biotechnol

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