Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy.

Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy. Research Abstract Details 

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Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy. Abstract Text:

Takafumi Taguchi,Tadashi Suehiro,Kagawa Toru,Naoko Ogami,Hiroshi Takata,Kozo Hashimoto,

We present the case of an elderly woman with myasthenia gravis who had pleural dissemination of thymoma reduced by treatments with a moderate dose of corticosteroids and a conventional dose of tacrolimus. A maintenance dose of prednisolone for myasthenia gravis could not shrink the size of the disseminated thymoma, but prednisolone (>30 mg daily) succeeded in reducing the size of the tumor. Moreover, a combination with tacrolimus enabled the daily dose of prednisolone to be tapered off without recurrence of myasthenia gravis, and the disseminated thymoma almost disappeared. A moderate or higher dosage of corticosteroids with tacrolimus may, in some cases, be an effective procedure for pleural dissemination of thymoma. Treatment should be undertaken on a trial basis for patients not indicated for surgery, radiotherapy, or chemotherapy.

Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy. Publishing Authors By Initials

T Taguchi,T Suehiro,K Toru,N Ogami,H Takata,K Hashimoto,

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Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of internal medicine

VOLUME: 17

Page Numbers: 575-7

Journal Abbreviation: Eur. J. Intern. Med.

ISSN: 0953-6205

DAY: 4

MONTH: Dec

YEAR: 2006

Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy. Information

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LANGUAGE: eng

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AFFILIATION: Departments of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Japan.

Country: Netherlands

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MEDLINETA: Eur J Intern Med

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