Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats.

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Abstract Text:

L Rasubala,H Yoshikawa,K Nagata,T Iijima,M Ohishi,

We studied the effects of platelet-derived growth factor-B (PDGF-B) and bone morphogenetic protein-2 (BMP-2) during the healing of mandibular closed fractures in rats by immunohistochemical methods. Unilateral closed fractures were created in the mandibles of thirty 12-week-old rats. BMP-2 was expressed during all stages of healing, but PDGF-B was expressed mainly in the early and middle stages, and not in the later stage of the healing process. We conclude that PDGF-B was associated with the proliferation and migration of primitive mesenchymal cells. BMP-2 was related to the differentiation of mesenchymal cells into osteoblasts and chondroblasts. PDGF-B and BMP-2 both have distinct regulatory effects on the healing of fractures.

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Publishing Authors By Initials

L Rasubala,H Yoshikawa,K Nagata,T Iijima,M Ohishi,

For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

PUBMED ID PMID:

MEDLINE DATE:

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of oral & maxillofacial surger

VOLUME: 41

Page Numbers: 173-8

Journal Abbreviation:

ISSN: 0266-4356

DAY: 19

MONTH: Jun

YEAR: 2003

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8405235

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Keywords Mesh Terms:

KEYWORDS: Transforming Growth Factor beta

MESH TERMS: physiology

Chemical & Substance for Abstract: Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats. Information

Substance Name: bone morphogenetic protein 2

Registry Number: 0

Grant and Affiliation Information for Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats.

AFFILIATION: Department of Oral and Maxillofacial Oncology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan. rasubala@isc.kyushu-u.ac.jp

Country: Scotland

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Br J Oral Maxillofac Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats Related Publications

• Absolute Structure of Kiwiionoside as a Precursor of Loliolide and Actinidiolide, from Actinidia chinensis.
• Comparison of the healing process in plated and non-plated fractures of the mandible in rats.
• Effect of ultrasound sonication on electroplating of iridium.
• Factors predictive of survival after percutaneous endoscopic gastrostomy in the elderly: is dementia really a risk factor?
• Incorporation of riboflavin into covalently-bound flavins in rat liver.
• Interference fringe signal generator and its application.
• Lifetime of the purple intermediate of D-amino acid oxidase under anaerobic conditions.
• Monomer-dimer equilibrium of D-amino-acid oxidase apoenzyme.
• Multiple Outbreaks of Gastroenteritis Due to a Single Strain of Genotype GII/4 Norovirus in Kobe, Japan, 2006: Risk Factors for Norovirus Spread in Health Care Settings.
• NAD-glycohydrolase activity of botulinum C2 toxin: a possible role of component I in the mode of action of the toxin.
• Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats.
• Possible mechanisms of diethyldithiocarbamate-induced gastro-duodenal mucosal damage in rats.
• Power dependence of Brillouin linewidths in a silica fiber.
• Preparation of 2-, 3-, 4- and 7-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b]furans and their BLT(1) and/or BLT(2) inhibitory activities.
• Preparation of 3-(4-chlorophenyl)-2-(2-aminothiazol-4-yl)-5-methoxybenzo[b]furan derivatives and their leukotriene B(4) inhibitory activity.
• Preparation of leukotriene B(4) inhibitory active 2- and 3-(2-aminothiazol-4-yl)benzo[b]furan derivatives and their growth inhibitory activity on human pancreatic cancer cells.
• Stable gain-switched 845 nm pulse generation by a weak 1550 nm seed laser.
• Syntheses of 3-acetoacetylaminobenzo[b]furan derivatives having cysteinyl leukotriene 2 receptor antagonistic activity.
• Widely tunable ring-cavity tellurite fiber Raman laser.
• [A case report of double orifice mitral valve (DOMV) associated with incomplete endocardial cushion defect (ECD)]
• [A study on the alteration of hemodynamics in patients with pulmonary operation and the signification of unilateral pulmonary artery occlusion test--using hemodynamogram]
• [Abnormal septal motion following non-surgical closure of the patent ductus arteriosus]
• [Cell mediated immune response following open heart surgery--the effect of cardiopulmonary bypass time]
• [Four operated cases of traumatic tricuspid regurgitation]
• [Left atrial free-floating ball thrombus in a patient without mitral valve disease]
• [Operation methods and results in repeated open heart surgery for acquired valvular disease]
• [Simultaneous operation for annulo-aortic ectasia, mitral regurgitation, and tricuspid regurgitation in a patient with Marfan syndrome--report of a case]
• [Surgical indication for the closure of atrial septal defects in patients over 30 years of age: retrospective study]