Plasma or serum in therapeutic drug monitoring and clinical toxicology.

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Abstract Text:

The relative merits of plasma and serum in blood analysis are reviewed. The expression 'plasma concentration' is often used in the literature, although serum samples have been taken. In most cases serum and plasma concentrations of analytes are the same. The choice depends mostly on the policy of the hospital or the availability of the test tubes in the ward. Some of the advantages of plasma over serum are large volume, no delayed clotting, less risk of haemolysis. In addition, the sample is often suitable for both whole blood and plasma monitoring. Some of the disadvantages of plasma over serum are the (unknown) influence of the anticoagulant on the assay, on the protein binding and on the stability of the sample, the (unknown) influence of additives or impurities in the anticoagulants on the assay and on the concentration, the risk of the formation of small clots and dilution of the sample.

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Publishing Authors By Initials

For similar pharmaceutical preparations research abstracts see: pharmaceutical preparations research

PUBMED ID PMID:

MEDLINE DATE:

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Journal Published:

PUBLICATION TYPE: Review

Journal: Pharmaceutisch weekblad. Scientific edition

VOLUME: 10

Page Numbers: 185-8

Journal Abbreviation:

ISSN: 0167-6555

DAY: 14

MONTH: Oct

YEAR: 1988

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Information

Number of References: 29

LANGUAGE: eng

NlmUniqueID: 7907992

Plasma or serum in therapeutic drug monitoring and clinical toxicology. Keywords Mesh Terms:

KEYWORDS: Pharmaceutical Preparations

MESH TERMS: blood

Chemical & Substance for Abstract: Plasma or serum in therapeutic drug monitoring and clinical toxicology. Information

Substance Name: Pharmaceutical Preparations

Registry Number: 0

Grant and Affiliation Information for Plasma or serum in therapeutic drug monitoring and clinical toxicology.

AFFILIATION: Department of Pharmacy, University Hospital Groningen.

Country: NETHERLANDS

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Pharm Weekbl Sci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Plasma or serum in therapeutic drug monitoring and clinical toxicology Related Publications

• Clinical and pharmaceutical aspects in acute poisoning.
• Plasma or serum in therapeutic drug monitoring and clinical toxicology.
• The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30 mg oxazepam.