Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia.

Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Research Abstract Details 

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Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Abstract Text:

OBJECTIVE: To determine whether nitric oxide production levels differ in patients with deficit and non-deficit forms of schizophrenia. METHODS: We investigated plasma nitrate levels, an index of in vivo nitric oxide production, in patients with deficit syndrome (n = 11) and non-deficit syndrome (n = 14) and healthy controls (n = 12) with a combination of high-performance liquid chromatography and the Griess reaction. RESULTS: There was no difference found in mean plasma nitrite levels, but plasma nitrate levels of patients with deficit syndrome were significantly lower than those with non-deficit syndrome (28.0 [SEM 2.5] micromol/L v. 44.2 [SEM 5.5] micromol/L, p < 0.05). CONCLUSIONS: A decline in nitric oxide production may be involved in primary negative symptoms in schizophrenia.

Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Publishing Authors By Initials

For similar behavioral disciplines and activities: schizophrenic psychology research abstracts see: behavioral disciplines and activities: schizophrenic psychology research

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Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of psychiatry & neuroscience : JPN

VOLUME: 28

Page Numbers: 288-92

Journal Abbreviation: J Psychiatry Neurosci

ISSN: 1180-4882

DAY: 6

MONTH: Jul

YEAR: 2003

Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Information

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LANGUAGE: eng

NlmUniqueID: 9107859

Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Keywords Mesh Terms:

KEYWORDS: Schizophrenic Psychology

MESH TERMS: metabolism

Chemical & Substance for Abstract: Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia. Information

Substance Name: Nitric Oxide

Registry Number: 10102-43-9

Grant and Affiliation Information for Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia.

AFFILIATION: Department of Psychiatry, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. e-suzuki@kitasato-u.ac.jp

Country: Canada

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MEDLINETA: J Psychiatry Neurosci

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