Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man.

Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Research Abstract Details 

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Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Abstract Text:

A P Niarchos,T G Pickering,A Morganti,J H Laragh,

The hemodynamic and plasma catecholamine responses to isometric exercise and head up tilt were investigated in normotensive and hypertensive subjects during normal and low sodium intake and before and during the administration of the converting enzyme inhibitors teprotide or captopril. Although teprotide and captopril decreased significantly the mean arterial pressure during both sodium intakes the normal pattern of hemodynamic response to hand grip and head up tilt was preserved. Moreover changes of plasma catecholamines during hand grip and head up tilt were not affected either by teprotide or captopril. When following the administration of teprotide or captopril fainting occurred either in the seated position or during head up tilt it was associated not only with a decrease in arterial pressure but also with a concurrent reduction in cardiac output and/or hypovolemia. It is concluded that converting enzyme inhibition does not impair significantly the cardiovascular responses which are mediated via the sympathetic nervous system either in normotensive or in hypertensive subjects.

Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Publishing Authors By Initials

AP Niarchos,TG Pickering,A Morganti,JH Laragh,

For similar peptides: oligopeptides: teprotide research abstracts see: peptides: oligopeptides: teprotide research

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Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Clinical and experimental hypertension. Part A, Th

VOLUME: 4

Page Numbers: 761-89

Journal Abbreviation:

ISSN: 0730-0077

DAY: 12

MONTH: 02

YEAR: 1982

Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8207790

Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Keywords Mesh Terms:

KEYWORDS: Teprotide

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Information

Substance Name: Sodium

Registry Number: 7440-23-5

Grant and Affiliation Information for Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man.

AFFILIATION:

Country: UNITED STATES

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MEDLINETA: Clin Exp Hypertens A

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