Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation.

Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Research Abstract Details 

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Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Abstract Text:

Takumi Yamada,Yoshimasa Murakami,Taro Okada,Naoki Yoshida,Junji Toyama,Yukihiko Yoshida,Naoya Tsuboi,Yasuya Inden,Makoto Hirai,Toyoaki Murohara,Takumi Yamada,Yoshimasa Murakami,Taro Okada,Naoki Yoshida,Junji Toyama,Yukihiko Yoshida,Naoya Tsuboi,Yasuya Inden,Makoto Hirai,Toyoaki Murohara,

AIMS: The aim of this study was to investigate the change in plasma brain natriuretic peptide (BNP) level after pulmonary vein isolation (PVI) in paroxysmal (PAF), persistent (Pers-AF), and permanent atrial fibrillation (AF) (Perm-AF) patients. METHODS AND RESULTS: In 96 lone AF patients (PAF=65, Pers-AF=17, and Perm-AF=14), BNP was measured before and 3 months after successful PVIs. At baseline, in all patients, BNP was elevated and was significantly greater in Pers-AF and Perm-AF patients than PAF patients (P<0.05). After 3 months of follow-up following multiple PVIs, AF recurred in 12 (18%) PAF, 7 (41%) Pers-AF, and 8 (57%) Perm-AF patients. In Pers-AF and Perm-AF patients, BNP at baseline did not predict AF recurrence. After the PVIs, BNP significantly decreased in PAF and Pers-AF patients (P=0.005) but not in Perm-AF patients. An elevated BNP at baseline decreased to within-normal limits in all Pers-AF and Perm-AF patients without AF recurrences. In all seven (23%) patients, whose AF type improved after the PVIs, BNP decreased. CONCLUSION: The reduction in the BNP level after the PVI seemed to be a marker for a good outcome in AF post-ablation patients.

Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Publishing Authors By Initials

T Yamada,Y Murakami,T Okada,N Yoshida,J Toyama,Y Yoshida,N Tsuboi,Y Inden,M Hirai,T Murohara,T Yamada,Y Murakami,T Okada,N Yoshida,J Toyama,Y Yoshida,N Tsuboi,Y Inden,M Hirai,T Murohara,

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Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Europace : European pacing, arrhythmias, and cardi

VOLUME: 9

Page Numbers: 770-4

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ISSN: 1099-5129

DAY: 1

MONTH: 08

YEAR: 2007

Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Information

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LANGUAGE: eng

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AFFILIATION: Cardiac Rhythm Management Laboratory, Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, AL 35294-0019, USA. takumi-y@fb4.so-net.ne.jp

Country: England

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