Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate.

Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Research Abstract Details 

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Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Abstract Text:

M Hidiroglou,K Singh,

The purpose of this study was to compare the bioavailability of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate when administered to sheep in a single oral dose weekly. The sheep, five per treatment, were given a basal diet without vitamin E supplement (control) or basal diet with weekly administration of 2225 IU of dl-alpha-tocopheryl acetate, 2225 IU of d-alpha-tocopheryl succinate, or 6675 IU of d-alpha-tocopheryl succinate. Increases in plasma alpha-tocopherol concentration levels over the 3-wk period of study were determined and compared. The greater availability of dl-alpha-tocopheryl acetate was indicated by the significantly higher peak plasma alpha-tocopherol concentrations and the greater area under the curve produced by administration of the acetate than the succinate esters at the same dosage. Reported data on plasma alpha-tocopherol concentrations suggest that bioavailability in sheep of d-alpha-tocopheryl succinate versus dl-alpha-tocopheryl acetate is 3:1.

Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Publishing Authors By Initials

M Hidiroglou,K Singh,

For similar heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research abstracts see: heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research

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Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of dairy science

VOLUME: 74

Page Numbers: 2718-23

Journal Abbreviation: J. Dairy Sci.

ISSN: 0022-0302

DAY: 19

MONTH: Aug

YEAR: 1991

Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Information

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LANGUAGE: eng

NlmUniqueID: 2985126

Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Keywords Mesh Terms:

KEYWORDS: alpha-Tocopherol

MESH TERMS: analogs & derivatives

Chemical & Substance for Abstract: Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate. Information

Substance Name: tocopherol acetate

Registry Number: 7695-91-2

Grant and Affiliation Information for Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl succinate.

AFFILIATION: Animal Research Centre, Agriculture Canada, Ottawa, ON.

Country: UNITED STATES

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MEDLINETA: J Dairy Sci

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