PKU in adolescents: rationale and psychosocial factors in diet continuation.

PKU in adolescents: rationale and psychosocial factors in diet continuation. Research Abstract Details 

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PKU in adolescents: rationale and psychosocial factors in diet continuation. Abstract Text:

Follow-up of early-treated children with PKU has shown that diet discontinuation in childhood presents risks of cognitive and emotional dysfunction in a substantial number of adolescents and young adults. This dysfunction includes IQ loss, mental processing abnormalities, learning difficulties, anxiety and personality disorders. In addition, neurologic deterioration has been reported in several such individuals. As a consequence of this current understanding of PKU, diet continuation, at least through adolescence and in the young adult years, is now recommended. Many centers are extending this to a policy of "diet for life". This represents a major challenge to adolescents and their families. Metabolic control using the criteria applied during childhood is virtually impossible to achieve past 12 years of age. Time constraints, social pressures, financial limitations and growing independence from the family combine to interfere with dietary control. Added to these difficulties are the biological changes during teenage years which reduce phenylalanine tolerance. To meet these challenges, we have identified a number of psychosocial factors that interfere with adherence to medical recommendations. The factors most highly related to metabolic control were social support for the diet and positive perceptions of treatment. This information has led to the development of support programs for adolescents and young adults with PKU.(ABSTRACT TRUNCATED AT 250 WORDS)

PKU in adolescents: rationale and psychosocial factors in diet continuation. Publishing Authors By Initials

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PKU in adolescents: rationale and psychosocial factors in diet continuation. Journal Published:

PUBLICATION TYPE: Review

Journal: Acta paediatrica (Oslo, Norway : 1992). Supplement

VOLUME: 407

Page Numbers: 92-7

Journal Abbreviation: Acta Paediatr Suppl

ISSN: 0803-5326

DAY: 12

MONTH: Dec

YEAR: 1994

PKU in adolescents: rationale and psychosocial factors in diet continuation. Information

Number of References: 30

LANGUAGE: eng

NlmUniqueID: 9315043

PKU in adolescents: rationale and psychosocial factors in diet continuation. Keywords Mesh Terms:

KEYWORDS: Social Support

MESH TERMS: psychology

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Grant and Affiliation Information for PKU in adolescents: rationale and psychosocial factors in diet continuation.

AFFILIATION: Biochemical Genetics Unit of the Division of Genetics, Children's Hospital, Boston, MA 02115, USA.

Country: NORWAY

AGENCY: United States NICHD

GRANT: N01-HD-2-3149

ACRONYM: HD

MEDLINETA: Acta Paediatr Suppl

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