Pioglitazone hydrochloride/glimepiride.

Pioglitazone hydrochloride/glimepiride. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Pioglitazone hydrochloride/glimepiride. Abstract Text:

Elizabeth W Blake,

The combination of pioglitazone hydrochloride, a thiazolidinedione, and glimepiride, a sulfonylurea, has been approved in many countries worldwide as an oral agent for the management of type 2 diabetes. Glimepiride stimulates insulin secretion from the pancreas with a decreased risk of hypoglycemia compared to glyburide. Pioglitazone increases glucose uptake in the periphery while decreasing glucose production by the liver. Combined, the two agents increase the body's sensitivity to insulin to reduce hemoglobin A1c levels by 1-2%. Pioglitazone and glimepiride also produce favorable effects on lipid profiles and blood pressure. Additionally, pioglitazone has proven to decrease the risk of certain cardiovascular events, providing evidence for macrovascular benefits. Side effects are minimal with pioglitazone and glimepiride, with weight gain and edema providing the most discomfort and complications. Patients must be monitored for the development of heart failure, though the risk is small. Guidelines are in place to limit patient selection for the use of pioglitazone based on cardiac risk factors. In general, pioglitazone and glimepiride are well tolerated.

Pioglitazone hydrochloride/glimepiride. Publishing Authors By Initials

EW Blake,

For similar thiazoles: thiazolidinediones research abstracts see: thiazoles: thiazolidinediones research

PUBMED ID PMID:

MEDLINE DATE:

Pioglitazone hydrochloride/glimepiride. Journal Published:

PUBLICATION TYPE: Review

Journal: Drugs of today (Barcelona, Spain : 1998)

VOLUME: 43

Page Numbers: 487-97

Journal Abbreviation: Drugs Today

ISSN: 1699-3993

DAY: 3

MONTH: Jul

YEAR: 2007

Pioglitazone hydrochloride/glimepiride. Information

Number of References: 49

LANGUAGE: eng

NlmUniqueID: 101160518

Pioglitazone hydrochloride/glimepiride. Keywords Mesh Terms:

KEYWORDS: Thiazolidinediones

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Pioglitazone hydrochloride/glimepiride. Information

Substance Name: glimepiride

Registry Number: 93479-97-1

Grant and Affiliation Information for Pioglitazone hydrochloride/glimepiride.

AFFILIATION: South Carolina College of Pharmacy, University of South Carolina Campus, Columbia, SC 29208, USA. blake@cop.sc.edu

Country: Spain

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Drugs Today (Barc)

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Pioglitazone hydrochloride/glimepiride Related Publications

• A comprehensive simulation for wait time reduction and capacity planning applied in general surgery.
• Assessing obsessive compulsive symptoms and cognitions on the internet: evidence for the comparability of paper and Internet administration.
• Be vigilant for symptoms of perinatal depression.
• Blood pressure, volume, and sodium control in an automated peritoneal dialysis population.
• Body perception disturbance: A contribution to pain in complex regional pain syndrome (CRPS).
• Byways of nomenclature.
• Covalent and noncovalent modifications induce allosteric binding behavior in a monoclonal antibody.
• Depth of interocular suppression associated with continuous flash suppression, flash suppression, and binocular rivalry.
• Education and workforce development issues associated with invisibility.
• Expression of sperm protein 22 (SP22) in the rat ovary during different reproductive states.
• Fearful expressions gain preferential access to awareness during continuous flash suppression.
• Illusory colors promote interocular grouping during binocular rivalry.
• Leiomyomata uteri: hormonal and molecular determinants of growth.
• Mode-partition noise interferometric conversion function.
• Navigated implantation after microsurgical bone transfer using intraoperatively acquired cone-beam computed tomography data sets.
• Neural bases of binocular rivalry.
• Ontology development for biological systems: immunology.
• Pathogenesis of renal dysfunction during congestive heart failure.
• Pioglitazone hydrochloride/glimepiride.
• Prefabricated autogenous ear cartilages.
• Randomized controlled trials in PD.
• Rapid synthesis of medium-ring fused polycarbocyclic systems by rearrangement of carbenoid-derived oxonium ylides.
• Reducing choice and fairness: the reality of WorkChoices.
• Revitalization: are we there yet?
• Somaesthetic disturbances in fibromyalgia are exaggerated by sensory motor conflict: implications for chronicity of the disease?
• Spatial grouping in human vision: temporal structure trumps temporal synchrony.
• Status of methodology for the determination of fat-soluble vitamins in foods, dietary supplements, and vitamin premixes.
• T-scores and z-scores.
• The effects of transcranial magnetic stimulation on visual rivalry.
• Voluntary action influences visual competition.