Phytochemical investigation of Tiarella polyphylla.

Phytochemical investigation of Tiarella polyphylla. Research Abstract Details 

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Phytochemical investigation of Tiarella polyphylla. Abstract Text:

Guanghai Shen,Sei-Ryang Oh,Byung-Sun Min,Joongku Lee,Kyung Seop Ahn,Young Ho Kim,Hyeong-Kyu Lee,

Seven flavonoids (1-7), two triterpenoids (8 and 9) and four steroids (10, 11, 12 and 13) were isolated from the whole plant of Tiarella polyphylla. Based on the physicochemical and spectroscopic analyses, their structures were identified as myricetin (1), astragalin (2), afzelin (3), quercitrin (4), myricitin (5), nicotiflorin (6), isoquercitrin (7), tiarellic acid (8), 3beta-hydroxy-20(29)lupen-27-oic acid (9), beta-sitosterol-3-O-beta-D-glucoside (10), stigmasterol-3-O-beta-D-glucoside (11), beta-sitosterol (12) and ergosterol endoperoxide (13). All 13 compounds, with the exception of tiarellic acid were isolated for the first time from T. polyphylla. In the anti-complementary assay, the steroids (12 and 13) exhibited potent activities; whereas, the flavonoids (1 to 7) showed weak or no activities, but even the triterpenoids (8 and 9) and steroidal saponins (10 and 11) evoked hemolysis.

Phytochemical investigation of Tiarella polyphylla. Publishing Authors By Initials

G Shen,SR Oh,BS Min,J Lee,KS Ahn,YH Kim,HK Lee,

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Phytochemical investigation of Tiarella polyphylla. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Archives of pharmacal research

VOLUME: 31

Page Numbers: 10-6

Journal Abbreviation: Arch. Pharm. Res.

ISSN: 0253-6269

DAY: 18

MONTH: Jan

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: College of Pharmacy, Yanbian University, Yanji 133000, PR China.

Country: Korea (South)

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MEDLINETA: Arch Pharm Res

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