Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants.

Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Research Abstract Details 

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Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Abstract Text:

David S Kwon,Melissa R Spevak,Kenneth Fletcher,Paul K Kleinman,

OBJECTIVE: The objective of our study was to determine the prevalence, distribution, and thickness of physiologic subperiosteal new bone formation in neonates and infants. MATERIALS AND METHODS: High-detail postmortem skeletal radiologic surveys of 101 neonates and infants who had died from sudden infant death syndrome were reviewed. The average age at the time of death was 2.6 months (range, 2 weeks-8 months 2 weeks). The location, distribution, and thickness of subperiosteal new bone formation of the long bones were noted and measured with an ocular magnification system. RESULTS: subperiosteal new bone formation was identified in 35 infants (35%), all of whom were between 1 and 4 months of age. The prevalence of subperiosteal new bone formation involving one or more bones was 37% for ages 1-2 months, 55% for ages 2-3 months, and 35% for ages 3-4 months. subperiosteal new bone formation involved the tibia in 29 infants (bilateral involvement in 19) and the femurs in 14 infants (bilateral involvement in 11). The humerus was a site of subperiosteal new bone formation in 12 infants; the ulna, in seven infants; and the radius, in two infants. The thickness of the subperiosteal new bone formation was never more than 1.8 mm, and the average thickness for the various long bones ranged from 0.7 to 0.9 mm. CONCLUSION: Our results suggest that subperiosteal new bone formation is a common finding in infants 1-4 months of age. It is potentially an abnormal finding in neonates (CI = 0.0, 0.007) and in infants older than 4 months of age (CI = 0.0, 0.003). A thickness of 2 mm or more in subperiosteal new bone formation is likely to be abnormal and should prompt further diagnostic evaluation.

Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Publishing Authors By Initials

DS Kwon,MR Spevak,K Fletcher,PK Kleinman,

For similar musculoskeletal system: skeleton: bone and bones: bones of lower extremity: leg bones: tibia research abstracts see: musculoskeletal system: skeleton: bone and bones: bones of lower extremity: leg bones: tibia research

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Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 179

Page Numbers: 985-8

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Oct

YEAR: 2002

Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants. Keywords Mesh Terms:

KEYWORDS: Tibia

MESH TERMS: radiography

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Grant and Affiliation Information for Physiologic subperiosteal new bone formation: prevalence, distribution, and thickness in neonates and infants.

AFFILIATION: Department of Radiology and Imaging Center for Child Abuse and Neglect, UMass Memorial Health Care, 55 Lake Avenue N., Worcester, MA 01655, USA.

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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