Physicochemical and immunological basis of silicone pathophysiology.

Physicochemical and immunological basis of silicone pathophysiology. Research Abstract Details 

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Physicochemical and immunological basis of silicone pathophysiology. Abstract Text:

N Kossovsky,C J Freiman,

Silicones, model biomaterials with almost ubiquitous applications, are the focus of a contentious debate. In this review, we will consider both established physicochemical phenomena and immunological phenomena; and then consider the human clinical phenomena that relate directly to them. We will explore the two competing theories of the biological activity of silicones, and we will discuss the weaknesses in the various arguments that silicone is inert. We conclude that from a pathophysiological perspective, silicones should be expected to be bioactive materials and that the physicochemical and immunological data at the experimental level are compelling.

Physicochemical and immunological basis of silicone pathophysiology. Publishing Authors By Initials

N Kossovsky,CJ Freiman,

For similar silicones research abstracts see: silicones research

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Physicochemical and immunological basis of silicone pathophysiology. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of biomaterials science. Polymer edition

VOLUME: 7

Page Numbers: 101-13

Journal Abbreviation:

ISSN: 0920-5063

DAY: 20

MONTH: 02

YEAR: 1995

Physicochemical and immunological basis of silicone pathophysiology. Information

Number of References: 91

LANGUAGE: eng

NlmUniqueID: 9007393

Physicochemical and immunological basis of silicone pathophysiology. Keywords Mesh Terms:

KEYWORDS: Silicones

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Physicochemical and immunological basis of silicone pathophysiology. Information

Substance Name: Silicones

Registry Number: 0

Grant and Affiliation Information for Physicochemical and immunological basis of silicone pathophysiology.

AFFILIATION: Department of Pathology and Laboratory Medicine, University of California, Los Angeles School of Medicine 90024-1732, USA.

Country: NETHERLANDS

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MEDLINETA: J Biomater Sci Polym Ed

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