Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions.

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Abstract Text:

Yuxin Pei,Hui Yu,Zhichao Pei,Matthias Theurer,Carolin Ammer,Sabine ,Hans-Joachim Gabius,Mingdi Yan,Olof ,Yuxin Pei,Hui Yu,Zhichao Pei,Matthias Theurer,Carolin Ammer,Sabine ,Hans-Joachim Gabius,Mingdi Yan,Olof ,

Photoderivatized polymer-coated gold surfaces have been developed following a perfluorophenylazide-based double ligation strategy. Gold-plated quartz crystal microbalance (QCM) crystals were initially covalently functionalized with a monolayer of poly(ethylene glycol) (PEG), using photo- or thermolytic nitrene formation and insertion. The polymer surfaces were subsequently used as substrates for photoinsertion of carbohydrate-derivatized photoprobes, yielding different recognition motifs for selective protein binding. The resulting robust and biocompatible sensor surfaces were applied to a flow-through QCM instrument for monitoring lectin-carbohydrate interactions in real time. The results clearly show the predicted lectin selectivity, demonstrating the applicability of the approach.

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Publishing Authors By Initials

Y Pei,H Yu,Z Pei,M Theurer,C Ammer,S ,HJ Gabius,M Yan,O ,Y Pei,H Yu,Z Pei,M Theurer,C Ammer,S ,HJ Gabius,M Yan,O ,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Analytical chemistry

VOLUME: 79

Page Numbers: 6897-902

Journal Abbreviation: Anal. Chem.

ISSN: 0003-2700

DAY: 18

MONTH: 08

YEAR: 2007

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370536

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions.

AFFILIATION: Department of Chemistry, KTH-Royal Institute of Technology, Teknikringen 30, S-10044 Stockholm, Sweden.

Country: United States

AGENCY: United States NIGMS

GRANT: 1R15 GM066279-01A2

ACRONYM: GM

MEDLINETA: Anal Chem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions Related Publications

• Contamination of oral wounds with saliva and bacteria.
• Crystallization-induced secondary selection from a tandem driven dynamic combinatorial resolution process.
• Fibrinolytic activity in the saliva of patients with coagulation disorders.
• Photoderivatized polymer thin films at quartz crystal microbalance surfaces: sensors for carbohydrate-protein interactions.
• Photogenerated carbohydrate microarrays.
• Study of real-time lectin-carbohydrate interactions on the surface of a quartz crystal microbalance.
• Supramolecular activation in triggered cascade inversion.
• Tandem driven dynamic combinatorial resolution via Henry-iminolactone rearrangement.