Phenotypic analysis of B-cells and plasma cells.

Phenotypic analysis of B-cells and plasma cells. Research Abstract Details 

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Phenotypic analysis of B-cells and plasma cells. Abstract Text:

Henrik E Mei,Taketoshi Yoshida,Gwendolin Muehlinghaus,Falk Hiepe,Thomas ,Andreas Radbruch,Bimba F Hoyer,Henrik E Mei,Taketoshi Yoshida,Gwendolin Muehlinghaus,Falk Hiepe,Thomas ,Andreas Radbruch,Bimba F Hoyer,

B-cells and antibody-secreting plasma cells are key players in protective immunity, but also in autoimmune disease. To understand their various functions in the initiation and maintenance of autoimmune pathology, a detailed dissection of their functional diversity is mandatory. This requires a detailed phenotypic classification of the diversity of B-cells. Here, technologies of immunocytometry and ELISpot are described in detail, and their value for phenotypic characterization of cells of the B lineage, as well as for preparative cell sorting, to further characterize them functionally and on the molecular level are described.

Phenotypic analysis of B-cells and plasma cells. Publishing Authors By Initials

HE Mei,T Yoshida,G Muehlinghaus,F Hiepe,T ,A Radbruch,BF Hoyer,HE Mei,T Yoshida,G Muehlinghaus,F Hiepe,T ,A Radbruch,BF Hoyer,

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Phenotypic analysis of B-cells and plasma cells. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Methods in molecular medicine

VOLUME: 136

Page Numbers: 3-18

Journal Abbreviation: Methods Mol. Med.

ISSN: 1543-1894

DAY: 6

MONTH: 11

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: German Rheumatism Research Centre, Berlin, Germany.

Country: United States

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MEDLINETA: Methods Mol Med

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