Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma.

Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Research Abstract Details 

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Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Abstract Text:

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem glioma (BSG). Children >/=3 and

Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Publishing Authors By Initials

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Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neuro-oncology

VOLUME: 10

Page Numbers: 341-7

Journal Abbreviation: Neuro-oncology

ISSN: 1522-8517

DAY: 16

MONTH: 04

YEAR: 2008

Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma.

AFFILIATION: Department of Radiation Oncology, 1600 Divisadero St., Suite H1031, San Francisco, CA 94115-1708. hkogan@radonc17.ucsf.edu.

Country: United States

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MEDLINETA: Neuro Oncol

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