Pharmacokinetics of antimicrobial agents in organ function impairment. A review.

Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Research Abstract Details 

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Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Abstract Text:

The pharmacokinetics of antimicrobial drugs in various types of organ function impairment are reviewed. The influence of renal function impairment on antimicrobial agents is well-known, although less is known about the accumulation of metabolites during renal failure. Fewer data are available on liver function impairment and more information is needed on highly metabolized agents. Pharmacokinetic studies in severely ill patients are urgently needed to investigate the influence of disease states on pharmacokinetics and to study the possibility of oral administration to seriously ill patients.

Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Publishing Authors By Initials

For similar digestive system diseases: liver diseases research abstracts see: digestive system diseases: liver diseases research

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Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Journal Published:

PUBLICATION TYPE: Review

Journal: Pharmaceutisch weekblad. Scientific edition

VOLUME: 12

Page Numbers: 121-7

Journal Abbreviation:

ISSN: 0167-6555

DAY: 24

MONTH: Aug

YEAR: 1990

Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Information

Number of References: 36

LANGUAGE: eng

NlmUniqueID: 7907992

Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Keywords Mesh Terms:

KEYWORDS: Liver Diseases

MESH TERMS: metabolism

Chemical & Substance for Abstract: Pharmacokinetics of antimicrobial agents in organ function impairment. A review. Information

Substance Name: Anti-Infective Agents

Registry Number: 0

Grant and Affiliation Information for Pharmacokinetics of antimicrobial agents in organ function impairment. A review.

AFFILIATION: Department of Clinical Pharmacy, Maasland Hospital, Sittard, The Netherlands.

Country: NETHERLANDS

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MEDLINETA: Pharm Weekbl Sci

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