Pharmacogenetics of chronic cardiovascular drugs: applications and implications.

Pharmacogenetics of chronic cardiovascular drugs: applications and implications. Research Abstract Details 

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Pharmacogenetics of chronic cardiovascular drugs: applications and implications. Abstract Text:

Issam Zineh,Julie A Johnson,

Cardiovascular disease continues to be a tremendous worldwide problem, and drug therapy is a major modality to attenuate its burden. At present, conditions such as hypertension, dyslipidaemia and heart failure are pharmacologically managed with an empirical trial-and-error approach. However, it has been suggested that this approach fails to adequately address the therapeutic needs of many patients, and pharmacogenetics has been offered as a tool to enhance patient-specific drug therapy. This review outlines pharmacogenetic studies of common cardiovascular drugs, such as diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, statins and warfarin, ultimately highlighting considerations for future research and practice.

Pharmacogenetics of chronic cardiovascular drugs: applications and implications. Publishing Authors By Initials

I Zineh,JA Johnson,

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Pharmacogenetics of chronic cardiovascular drugs: applications and implications. Journal Published:

PUBLICATION TYPE: Review

Journal: Expert opinion on pharmacotherapy

VOLUME: 7

Page Numbers: 1417-27

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ISSN: 1744-7666

DAY: 3

MONTH: Aug

YEAR: 2006

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LANGUAGE: eng

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Grant and Affiliation Information for Pharmacogenetics of chronic cardiovascular drugs: applications and implications.

AFFILIATION: University of Florida College of Pharmacy, Department of Pharmacy Practice and Center for Pharmacogenomics, 1600 SW Archer Rd., Room PG-06, PO Box 100486, Gainesville, FL 32610, USA. zineh@cop.ufl.edu

Country: England

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MEDLINETA: Expert Opin Pharmacother

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