Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow.

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Abstract Text:

Hwa Jung Sung,Seok Jin Kim,Ji Hye Lee,Goeun Lee,Kyung A Lee,Chul Won Choi,Byung Soo Kim,Jun Suk Kim,Hwa Jung Sung,Seok Jin Kim,Ji Hye Lee,Goeun Lee,Kyung A Lee,Chul Won Choi,Byung Soo Kim,Jun Suk Kim,Hwa Jung Sung,Seok Jin Kim,Ji Hye Lee,Goeun Lee,Kyung A Lee,Chul Won Choi,Byung Soo Kim,Jun Suk Kim,Hwa Jung Sung,Seok Jin Kim,Ji Hye Lee,Goeun Lee,Kyung A Lee,Chul Won Choi,Byung Soo Kim,Jun Suk Kim,

We report a case of pure red cell aplasia (PRCA), which was initially suspected as a result of bone marrow involvement of diffuse large B cell lymphoma. Persistent anemia without an obvious cause was observed in a 47-yr-old man diagnosed with relapsed diffuse large B cell lymphoma. The bone marrow study showed only erythroid hypoplasia without the evidence of bone marrow involvement with lymphoma cells, thus PRCA was suggested. However, parvovirus infection was excluded as a potential cause of PRCA because of negative IgM anti-parvovirus B19 antibody and negative parvovirus PCR in the serum. Latent Epstein-Barr virus (EBV) infection of bone marrow was suggested by in situ hybridization with EBV-encoded small RNA (EBER) that showed a strong positive expression in bone marrow cells. Thus, PRCA was thought to be associated with latent EBV infection in bone marrow cells. Although the finding of unexplained anemia is a possible predictor of bone marrow involvement with lymphoma cells, PRCA as a result of a viral infection including EBV should be considered in lymphoma patients. This is the first report of the occurrence of PRCA associated with latent EBV infection in a patient with non-Hodgkin's lymphoma.

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Publishing Authors By Initials

HJ Sung,SJ Kim,JH Lee,G Lee,KA Lee,CW Choi,BS Kim,JS Kim,HJ Sung,SJ Kim,JH Lee,G Lee,KA Lee,CW Choi,BS Kim,JS Kim,HJ Sung,SJ Kim,JH Lee,G Lee,KA Lee,CW Choi,BS Kim,JS Kim,HJ Sung,SJ Kim,JH Lee,G Lee,KA Lee,CW Choi,BS Kim,JS Kim,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of Korean medical science

VOLUME: 22 Suppl

Page Numbers: S167-70

Journal Abbreviation: J. Korean Med. Sci.

ISSN: 1011-8934

DAY: 9

MONTH: Sep

YEAR: 2007

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8703518

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow.

AFFILIATION: Division of Hematology and Oncology, Department of Internal Medicine, Korea University Medical Center, Seoul, Korea.

Country: Korea (South)

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Korean Med Sci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Persistent anemia in a patient with diffuse large B cell lymphoma: pure red cell aplasia associated with latent epstein-barr virus infection in bone marrow Related Publications

• Aberrant expression of MUC3 and MUC4 membrane-associated mucins and sialyl Le(x) antigen in pancreatic intraepithelial neoplasia.
• Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.
• Advanced capabilities for future light sources.
• Aging of the population and the subsequent increase in the mistreatment of the elderly in Korea.
• Alkali-catalyzed beta-elimination of periodate-oxidized glycans: a novel method of chemical deglycosylation of mucin gene products in paraffin embedded sections.
• Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence.
• Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells.
• Biological properties and expression of mucins in 5-fluorouracil resistant HT29 human colon cancer cells.
• Cholangiocarcinomas arising in cirrhosis and combined hepatocellular-cholangiocellular carcinomas share apomucin profiles.
• Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans.
• Drynariae Rhizoma promotes osteoblast differentiation and mineralization in MC3T3-E1 cells through regulation of bone morphogenetic protein-2, alkaline phosphatase, type I collagen and collagenase-1.
• Elderly Women's Grief in Korea.
• Expression of MUC2, MUC5AC and MUC6 apomucins in carcinoma, dysplasia and non-dysplastic epithelia of the gallbladder.
• Goblet cell-specific expression mediated by the MUC2 mucin gene promoter in the intestine of transgenic mice.
• Identification and characterization of the MUC2 (human intestinal mucin) gene 5'-flanking region: promoter activity in cultured cells.
• Immunohistochemical study of mucin carbohydrates and core proteins in hepatolithiasis and cholangiocarcinoma.
• Induction of mucin gene expression in middle ear of rats by tumor necrosis factor-alpha: potential cause for mucoid otitis media.
• Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.
• MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.
• Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.
• Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.
• Monoclonal antibodies against partially deglycosylated colon cancer mucin that recognize Tn antigen.
• Mouse intestinal goblet cells expressing SV40 T antigen directed by the MUC2 mucin gene promoter undergo apoptosis upon migration to the villi.
• Optical design of the U7 undulator beamline at the Pohang Light Source.
• Phorbol 12-myristate 13-acetate induces alteration in mucin gene expression and biological properties of colon cancer cells.
• Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kappa B.
• Stent-graft placement in a traumatic internal carotid-internal jugular fistula and pseudoaneurysm.
• Stereotactic aspiration of intracerebral haematoma: significance of surgical timing and haematoma volume reduction.
• Study of the aging perception.
• The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.