Persistence length measurements from stochastic single-microtubule trajectories.

Persistence length measurements from stochastic single-microtubule trajectories. Research Abstract Details 

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Persistence length measurements from stochastic single-microtubule trajectories. Abstract Text:

M G L van den Heuvel,S Bolhuis,C Dekker,M G L van den Heuvel,S Bolhuis,C Dekker,

We present a simple method to determine the persistence length of short submicrometer microtubule ends from their stochastic trajectories on kinesin-coated surfaces. The tangent angle of a microtubule trajectory is similar to a random walk, which is solely determined by the stiffness of the leading tip and the velocity of the microtubule. We demonstrate that even a single-microtubule trajectory suffices to obtain a reliable value of the persistence length. We do this by calculating the variance in the tangent trajectory angle of an individual microtubule. By averaging over many individual microtubule trajectories, we find that the persistence length of microtubule tips is 0.24 +/- 0.03 mm.

Persistence length measurements from stochastic single-microtubule trajectories. Publishing Authors By Initials

MG van den Heuvel,S Bolhuis,C Dekker,MG van den Heuvel,S Bolhuis,C Dekker,

For similar biomechanics: stress, mechanical research abstracts see: biomechanics: stress, mechanical research

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Persistence length measurements from stochastic single-microtubule trajectories. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nano letters

VOLUME: 7

Page Numbers: 3138-44

Journal Abbreviation: Nano Lett.

ISSN: 1530-6984

DAY: 21

MONTH: 09

YEAR: 2007

Persistence length measurements from stochastic single-microtubule trajectories. Information

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LANGUAGE: eng

NlmUniqueID: 101088070

Persistence length measurements from stochastic single-microtubule trajectories. Keywords Mesh Terms:

KEYWORDS: Stress, Mechanical

MESH TERMS: chemistry

Chemical & Substance for Abstract: Persistence length measurements from stochastic single-microtubule trajectories. Information

Substance Name: Molecular Motor Proteins

Registry Number: 0

Grant and Affiliation Information for Persistence length measurements from stochastic single-microtubule trajectories.

AFFILIATION: Kavli Institute of Nanoscience, Section Molecular Biophysics, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.

Country: United States

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MEDLINETA: Nano Lett

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