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Peroxidoxins: a new antioxidant family.

Peroxidoxins: a new antioxidant family. Research Abstract Details 

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  • Peroxidoxins: a new antioxidant family. Abstract Text:

    s mcgonigleS McGonigle,j p daltonJ P Dalton,e r jamesE R James,

    Peroxidoxins are a recently described family of antioxidants. They have an ancient origin, being present in organisms as primitive as the archaea, and they appear to be ubiquitous in living cells. Here, Sharon McGonigle, John Dalton and Eric James review the present understanding of the functions and mechanism of action of these enzymes and suggest that these antioxidants may represent the ;missing link' in the metabolism of reactive oxygen species by some protozoan and helminth parasites. Also, by performing sequence comparisons of homologues entered in the public databases, they have classified the parasite peroxidoxins as 1-cys or 2-cys enzymes. The discovery of these antioxidants may change our understanding of how reactive oxygen species, of parasite or host origin, are managed by parasites.

    Peroxidoxins: a new antioxidant family. Publishing Authors By Initials

    s mcgonigleS McGonigle,jp daltonJP Dalton,er jamesER James,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

    MEDLINE DATE:

    Peroxidoxins: a new antioxidant family. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Parasitology today (Personal ed.)

    VOLUME: 14

    Page Numbers: 139-45

    Journal Abbreviation: Parasitol. Today (Regul. Ed.)

    ISSN: 0169-4758

    DAY: 16

    MONTH: Apr

    YEAR: 1998

    Peroxidoxins: a new antioxidant family. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8605563

    Peroxidoxins: a new antioxidant family. Keywords Mesh Terms:

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    Chemical & Substance for Abstract: Peroxidoxins: a new antioxidant family. Information

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    Grant and Affiliation Information for Peroxidoxins: a new antioxidant family.

    AFFILIATION: Department of Ophthalmology, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC 29425, USA.

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Parasitol Today

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