Perinatal aspects of iron metabolism.

Perinatal aspects of iron metabolism. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Perinatal aspects of iron metabolism. Abstract Text:

Iron sufficiency is critical for rapidly developing fetal and neonatal organ systems. The majority of iron in the third trimester fetus and the neonate is found in the red cell mass (as hemoglobin), with lesser amounts in the tissues as storage iron (e.g. ferritin) or functional iron (e.g. myoglobin, cytochromes). Iron is prioritized to hemoglobin synthesis in red cells when iron supply does not meet iron demand. Thus, non-heme tissues such as the skeletal muscle, heart and brain will become iron deficient before signs of iron-deficiency anemia. Gestational conditions that result in lower newborn iron stores include severe maternal iron deficiency, maternal hypertension with intrauterine growth retardation and maternal diabetes mellitus. Stable, very low birthweight premature infants are also at risk for early postnatal iron deficiency because they accrete less iron during gestation, grow more rapidly postnatally, are typically undertreated with enteral iron and receive fewer red cell transfusions. Conversely, iron overload remains a significant concern in multiply transfused sick preterm infants because they have low levels of iron-binding proteins and immature antioxidant systems. CONCLUSION: The highly variable iron status of preterm infants combined with their risk for iron deficiency and toxicity warrants careful monitoring and support in the newborn and postdischarge periods.

Perinatal aspects of iron metabolism. Publishing Authors By Initials

For similar investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research abstracts see: investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research

PUBMED ID PMID:

MEDLINE DATE:

Perinatal aspects of iron metabolism. Journal Published:

PUBLICATION TYPE: Review

Journal: Acta paediatrica (Oslo, Norway : 1992). Supplement

VOLUME: 91

Page Numbers: 124-9

Journal Abbreviation: Acta Paediatr Suppl

ISSN: 0803-5326

DAY: 12

MONTH: 05

YEAR: 2002

Perinatal aspects of iron metabolism. Information

Number of References: 48

LANGUAGE: eng

NlmUniqueID: 9315043

Perinatal aspects of iron metabolism. Keywords Mesh Terms:

KEYWORDS: Severity of Illness Index

MESH TERMS: prevention & control

Chemical & Substance for Abstract: Perinatal aspects of iron metabolism. Information

Substance Name: Iron Compounds

Registry Number: 0

Grant and Affiliation Information for Perinatal aspects of iron metabolism.

AFFILIATION: Division of Neonatology, Department of Pediatrics and Center for Neurobehavioral Development, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA.

Country: Norway

AGENCY: United States NICHD

GRANT: HD-29421

ACRONYM: HD

MEDLINETA: Acta Paediatr Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Perinatal aspects of iron metabolism Related Publications

• Dissociating the long-term effects of fetal/neonatal iron deficiency on three types of learning in the rat.
• Gaze discrimination is unimpaired in schizophrenia.
• Iron deficiency in international adoptees from eastern europe.
• Iron in fetal and neonatal nutrition.
• Perinatal aspects of iron metabolism.
• Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia.
• Perinatal iron deficiency results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus.
• The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations.