Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis.

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Abstract Text:

Yoshihisa Tsuji,Hiroshi Yamamoto,Shujiro Yazumi,Yuji Watanabe,Kazuhiro Matsueda,Hiroyuki Yamamoto,Tsutomu Chiba,Yoshihisa Tsuji,Hiroshi Yamamoto,Shujiro Yazumi,Yuji Watanabe,Kazuhiro Matsueda,Hiroyuki Yamamoto,Tsutomu Chiba,Yoshihisa Tsuji,Hiroshi Yamamoto,Shujiro Yazumi,Yuji Watanabe,Kazuhiro Matsueda,Hiroyuki Yamamoto,Tsutomu Chiba,

BACKGROUND & AIMS: The mortality rate associated with severe acute pancreatitis (SAP) with necrosis remains high because early prediction of pancreatic necrosis is difficult. We evaluated whether perfusion computerized tomography (CT), which is used to identify early stage ischemia in the brain, could detect ischemic changes in the pancreas in the early stages of SAP and predict development of necrosis. PATIENTS AND METHODS: Thirty consecutive patients with a diagnosis of SAP according to the Atlanta criteria and whose score was greater than 6 were enrolled in this study. All patients were hospitalized within 3 days after onset of symptoms indicative of acute pancreatitis and underwent perfusion CT. Three weeks later, all patients underwent conventional contrast-enhanced CT to detect progression of their disease. RESULTS: Perfusion CT showed that 10 of the 30 patients had pancreatic ischemia at the time of diagnosis. Contrast-enhanced CT disclosed that pancreatic necrosis developed in 9 of these 10 patients, but not in the 20 patients who did not have pancreatic ischemia. The sensitivity and specificity of perfusion CT for predicting pancreatic necrosis was calculated to be 100% and 95.3%, respectively. CONCLUSIONS: Perfusion CT is a useful tool for early detection of ischemic changes in the pancreas that lead to pancreatic necrosis.

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Publishing Authors By Initials

Y Tsuji,H Yamamoto,S Yazumi,Y Watanabe,K Matsueda,H Yamamoto,T Chiba,Y Tsuji,H Yamamoto,S Yazumi,Y Watanabe,K Matsueda,H Yamamoto,T Chiba,Y Tsuji,H Yamamoto,S Yazumi,Y Watanabe,K Matsueda,H Yamamoto,T Chiba,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Clinical gastroenterology and hepatology : the off

VOLUME: 5

Page Numbers: 1484-92

Journal Abbreviation: Clin. Gastroenterol. Hepatol.

ISSN: 1542-7714

DAY: 22

MONTH: 10

YEAR: 2007

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101160775

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis.

AFFILIATION: Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Clin Gastroenterol Hepatol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis Related Publications

• Allosteric properties, substrate specificity, and subsite affinities of honeybee alpha-glucosidase I.
• Alterations in glucocorticoid receptor conformation by molybdate.
• Attenuated aerobic exercise capacity in CD36 deficiency.
• Changes in chromatin template activity for in vitro transcription during the development of the rat mammary gland.
• Determination of cadmium in grains by isotope dilution ICP-MS and coprecipitation using sample constituents as carrier precipitants.
• Diagnosis and treatment of obscure GI bleeding with double balloon endoscopy.
• Effects of sexual experience on conspecific odor preference and male odor-induced activation of the vomeronasal projection pathway and the nucleus accumbens in female rats.
• Electrocatalytic formal [2+2] cycloaddition reactions between anodically activated enyloxy benzene and alkenes.
• Essential arginyl residues in yeast phosphoglyceromutase.
• Evidence for a single catalytic site of honeybee alpha-glucosidase I by chemical modification with diethylpyrocarbonate.
• Fetal hydrothorax resolving completely after a single thoracentesis: a report of 2 cases.
• Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.
• Hepatocyte Nuclear Factor 1 Alpha is a Factor Responsible for the Interindividual Variation of OATP1B1 mRNA Levels in Adult Japanese Livers.
• Hepatocyte nuclear factor 1 alpha and 4 alpha are factors involved in interindividual variability in the expression of UGT1A6 and UGT1A9 but not UGT1A1, UGT1A3 and UGT1A4 mRNA in human livers.
• Kinetic studies on the substrate specificity and active site of rabbit muscle acid alpha-glucosidase.
• Lipofuscin bodies in human oocytes as an indicator of oocyte quality.
• Localization of bovine liver aldehyde dehydrogenase isozymes and their immunological properties.
• Mechanisms of inhibition and activation of beef liver D-glycerate dehydrogenase by inorganic anions.
• Molecular cloning of cDNA for trehalase from the European honeybee, Apis mellifera L., and its heterologous expression in Pichia pastoris.
• Molecular cloning of cDNAs and genes for three alpha-glucosidases from European honeybees, Apis mellifera L., and heterologous production of recombinant enzymes in Pichia pastoris.
• Occurrence of common binding sites for progestin and glucocorticoid in the lactating mammary gland of the rat.
• Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis.
• Purification and properties of beef liver D-glycerate dehydrogenase.
• Regulation of glucose 1,6-bisphosphate level in liver. III. Purification and properties of bovine glucose 1,6-bisphosphate synthase.
• Single active site mechanism of rabbit liver acid alpha-glucosidase.
• Slit and Robo control the development of dendrites in Drosophila CNS.
• Substrate specificity and subsite affinities of rabbit liver acid alpha-glucosidase.
• Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies.
• [A new orally active anti-rheumatic drug targets IL-15 and IL-17]
• [Prevention and treatment of nonsteroidal anti-inflammatory drug-induced gastric ulcers with proton pump inhibitor]