The possibilities of pseudo-peptide-DNA mimics like PNA (peptide nucleic acid) having a role for the prebiotic origin of life prior to an RNA world is discussed on the basis of literature data showing that this type of molecules might have formed on the primitive earth (or other places in the universe), as well as data indicating the possibilities of template-directed PNA chemical replication and ligation. In particular, the merits of an achiral prebiotic genetic material is discussed.
Peptide nucleic acids and the origin of life. Publishing Authors By Initials
Peptide nucleic acids and the origin of life. Journal Published:
PUBLICATION TYPE: Review
Journal: Chemistry & biodiversity
VOLUME: 4
Page Numbers: 1996-2002
Journal Abbreviation: Chem. Biodivers.
ISSN: 1612-1880
DAY: 20
MONTH: Sep
YEAR: 2007
Peptide nucleic acids and the origin of life. Information
Number of References: 22
LANGUAGE: eng
NlmUniqueID: 101197449
Peptide nucleic acids and the origin of life. Keywords Mesh Terms:
KEYWORDS: Protein Conformation
MESH TERMS: chemistry
Chemical & Substance for Abstract: Peptide nucleic acids and the origin of life. Information
Substance Name: Peptide Nucleic Acids
Registry Number: 0
Grant and Affiliation Information for Peptide nucleic acids and the origin of life.
AFFILIATION: Department of Cellular and Molecular Medicine, University of Copenhagen, The Panum Institute, Blegdamsvej 3c, DK-2200 Copenhagen N. pen@imbg.ku.dk
Country: Switzerland
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MEDLINETA: Chem Biodivers
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