Pathogenic aspects of cutaneous photoaging.

Pathogenic aspects of cutaneous photoaging. Research Abstract Details 

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Pathogenic aspects of cutaneous photoaging. Abstract Text:

Rachel E B Watson,Christopher E M Griffiths,

Chronic exposure to solar ultraviolet irradiation can result in wrinkle formation in many individuals. Wrinkling appears to be the conclusion of mechanisms that result in decreased synthesis of extracellular matrix molecules within the dermis, accompanied by increased remodeling of the matrix by specific endopeptidases (matrix metalloproteinases) and proteases (originating from infiltrating cells of the immune system). In this review, we discuss the changes that occur in the extracellular matrix of photoaged skin and the mechanisms by which they are modulated.

Pathogenic aspects of cutaneous photoaging. Publishing Authors By Initials

RE Watson,CE Griffiths,

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Pathogenic aspects of cutaneous photoaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of cosmetic dermatology

VOLUME: 4

Page Numbers: 230-6

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ISSN: 1473-2165

DAY: 15

MONTH: Dec

YEAR: 2005

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LANGUAGE: eng

NlmUniqueID: 101130964

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AFFILIATION: Dermatopharmacology Unit, Dermatology Centre, University of Manchester, Hope Hospital, Manchester, UK.

Country: England

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MEDLINETA: J Cosmet Dermatol

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