Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets.

Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Research Abstract Details 

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Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Abstract Text:

J Vítovec,B Koudela,M Kudweis,J St?pánek,B Smíd,R Dvorák,

51 gnotobiotic and 63 conventional, one-, or two-days-old piglets were divided into five groups and infected orally either with Isospora suis or rotavirus alone, or with both agents simultaneously or successively with alternative sequences and various intervals. 15 gnotobiotic and 10 conventional piglets served as controls. The development of small intestinal lesions after infection with I. suis was biphasic. The dominant alteration resulting from rotavirus infection was villus atrophy, considerably more pronounced and extensive in gnotobiotic than in conventional piglets. Synergistic action of I. suis and rotavirus was manifested both clinically, and morphologically. This action culminated at the time of the actual, or presumed development of merogony of I. suis, i.e. on DPI 3 to 5. The action develops only if the intestinal epithelium is damaged functionally and morphologically by a preceding rotavirus infection. It is concluded that the synergistic action is based on a competition of rotavirus and I. suis for mature, enzymatically active absorptive cells.

Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Publishing Authors By Initials

J Vítovec,B Koudela,M Kudweis,J St?pánek,B Smíd,R Dvorák,

For similar animal diseases: swine diseases research abstracts see: animal diseases: swine diseases research

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Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 38

Page Numbers: 215-26

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: May

YEAR: 1991

Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Information

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LANGUAGE: eng

NlmUniqueID: 331325

Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets. Keywords Mesh Terms:

KEYWORDS: Swine Diseases

MESH TERMS: pathology

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Grant and Affiliation Information for Pathogenesis of experimental combined infections with Isospora suis and rotavirus in conventional and gnotobiotic piglets.

AFFILIATION: Institut of Parasitology, Czechoslovak Academy of Sciences, Ceské Bud?jovice.

Country: GERMANY

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MEDLINETA: Zentralbl Veterinarmed B

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