Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'.

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Abstract Text:

Yasmin Bhurgri,Kauser Nazir,Yasmeen Shaheen,Ahmed Usman,Naveen Faridi,Hadi Bhurgri,Jawaid Malik,Imtiaz Bashir,Asif Bhurgri,Sheema H Hasan,Naila Kayani,Shm Zaidi,

Aim: To provide demographics and pathology of cancer of the uterine corpus in Karachi. Methodology: Data for 66 incident cases of cancer corpus uteri, ICD-10 category C54-5 registered at the Karachi Cancer Registry, for Karachi South, during a 3 year period, 1st January, 1995 to 31st December 1997 were reviewed. Results: Cancer uterine corpus (1995-97) was the sixth most common malignancy, following breast, oral cavity, ovary, esophagus and cervix. The age standardized incidence rate (ASR) world and crude incidence rate (CIR) per 100,000 were 6.4 (4.73 to 8.01) and 2.9 (2.18 to 3.57). The mean age was 53.7 years (SD 15.6; range 6-90 years). Fifty eight cases were endometrial carcinoma with ASR world and CIR per 100,000 of 5.77 (4.20 to 7.33) and 2.53 (1.88 to 3.18) respectively. Sarcomas comprised 6% of the cases. Approximately a third of the females (28.8%) were below 50 years of age. The age-specific curves showed a gradual increase from the fourth till the seventh decade, followed by an actual apparent decrease in risk after 70 years. Peak incidence was observed in the 65-69 year age group. Presenting symptoms were post-menopausal bleeding (86.4%) and purulent discharge (4%). Associated pathologies included adenomyosis, adenomatous hyperplasia (12% each) or leiomyoma (8%). Associated clinical conditions were diabetes mellitus and hypertension (4% each). The majority of the cases presented as well differentiated (39.4%), localized (59.1%) lesions. Conclusion: The incidence of cancer corpus uteri in Karachi South reflects a moderate risk population, predominantly middle aged with a higher socio-economic status. On the average the malignancy is observed a decade earlier then reported elsewhere. This calls for in-depth investigation of risk factors and identification of underlying etiology.

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Publishing Authors By Initials

Y Bhurgri,K Nazir,Y Shaheen,A Usman,N Faridi,H Bhurgri,J Malik,I Bashir,A Bhurgri,SH Hasan,N Kayani,S Zaidi,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE: 2007 Oct-Dec

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Asian Pacific journal of cancer prevention : APJCP

VOLUME: 8

Page Numbers: 489-94

Journal Abbreviation: Asian Pac. J. Cancer Prev.

ISSN: 1513-7368

DAY: 11

MONTH: 02

YEAR: 2008

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101130625

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'.

AFFILIATION: Pathology & Microbiology Department, Agakhan University, Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan. Email: bhurgri@cyber.net.pk.

Country: Thailand

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Asian Pac J Cancer Prev

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997' Related Publications

• Bone Loss in Thyroid Disease: Role of Low TSH and High Thyroid Hormone.
• CD38 is required for priming by TNF-alpha: a mechanism for extracellular coordination of cell fate.
• Calcium signalling and calcium transport in bone disease.
• Cellular and Molecular Consequences of Calcineurin A{alpha} Gene Deletion.
• Childhood cancer in Pakistan, with special reference to retinoblastoma.
• Chromium-reducing and plant growth-promoting Mesorhizobium improves chickpea growth in chromium-amended soil.
• Control of poliomyelitis in Kuwait.
• Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma.
• Effect of metal tolerant plant growth promoting Bradyrhizobium sp. (vigna) on growth, symbiosis, seed yield and metal uptake by greengram plants.
• Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts.
• Fifty years of progress in gynecologic ultrasound.
• Frequency of malignant tumours in Jinnah Postgraduate Medical Centre, Karachi.
• Fundamental failures of shape constancy resulting from cortical anisotropy.
• Habits and dietary pattern of cases of carcinoma of the oral cavity and oropharynx.
• Haematocolpos as a cause of urinary retention in the young female.
• Hollow visceral myopathy in a 5-year old boy: a case report.
• Molecular physiology and pharmacology of calcitonin.
• Neural basis of 3-D shape aftereffects.
• Osteoclastic differentiation and function regulated by old and new pathways.
• Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion.
• Patho-epidemiology of Cancer Cervix in Karachi South.
• Patho-epidemiology of Cancer Corpus Uteri in Karachi South '1995-1997'.
• Patho-epidemiology of breast cancer in Karachi '1995-1997'.
• Prediction of stability factors at the domain interface of human gammaB crystallin maintaining the transparency of the eye lens.
• Preparation, properties and infrared spectral studies of N-(p-ethylphenyl)thiobenzohydroxamic acid.
• Primary liver cancer in Pakistan.
• Similarities and contrasts in ryanodine receptor localization and function in osteoclasts and striated muscle cells.
• Skeletal remodeling in health and disease.
• The second conference on skeletal medicine and biology: overview and some comments.
• The second conference on skeletal medicine and biology: special features.