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Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated).

Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated). Research Abstract Details 

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  • Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated). Abstract Text:

    s al-sabahS Al-Sabah,p goldbergP Goldberg,s t qureshiS T Qureshi,s al-sabahS Al-Sabah,p goldbergP Goldberg,s t qureshiS T Qureshi,

    Severe sepsis and progression to septic shock in solid organ transplant recipients is associated with a high mortality. We describe a fulminant case of septic shock in a liver transplant recipient caused by Pasteurella multocida, a gram-negative coccobacillus most commonly associated with domestic cats and dogs. P. multocida is a rare cause of bacteremia and has not been reported as a cause of septic shock following liver transplantation. In addition to standard therapy, the patient was managed with drotrecogin alpha (activated) recombinant activated protein C (APC), an evidence-based agent that has been shown to significantly improve outcome in severe sepsis in the non-transplant population. The known risk factors, clinical course, and outcomes of severe infection associated with P. multocida are also briefly reviewed. This case illustrates the need for transplant recipients and their healthcare providers to carefully consider the risk of severe infection associated with domestic animal exposure.

    Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated). Publishing Authors By Initials

    s al-sabahS Al-Sabah,p goldbergP Goldberg,st qureshiST Qureshi,s al-sabahS Al-Sabah,p goldbergP Goldberg,st qureshiST Qureshi,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

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    Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated). Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Transplant infectious disease : an official journa

    VOLUME: 9

    Page Numbers: 233-6

    Journal Abbreviation:

    ISSN: 1398-2273

    DAY: 13

    MONTH: Sep

    YEAR: 2007

    Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated). Information

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    LANGUAGE: eng

    NlmUniqueID: 100883688

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    Grant and Affiliation Information for Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated).

    AFFILIATION: Department of Surgery, McGill University, Montreal, Quebec, Canada.

    Country: Denmark

    Denmark Research PublicationDenmark Research Publication

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    MEDLINETA: Transpl Infect Dis

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