Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex.

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Research Abstract Details 

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Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Abstract Text:

T Ogishima,Y Okada,S Kominami,S Takemori,T Omura,

Partial amino acid sequences of two mitochondrial cytochrome P-450's, P-450 (SCC) and P-450 (11 beta), and two microsomal cytochrome P-450's, P-450 (C-21), and P-450 (17 alpha, Lyase), from adrenal cortex were analyzed and compared. Mitochondrial P-450's and microsomal P-450's were different in the amino acid sequences at their NH2-terminals. The sequences of microsomal P-450's started from terminal methionine and were highly hydrophobic, whereas those of mitochondrial P-450's lacked NH2-terminal methionine and were not hydrophobic. These findings strongly suggest that the NH2-terminal portions of newly synthesized P-450's determine their intracellular localization to different cell organelles.

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Publishing Authors By Initials

T Ogishima,Y Okada,S Kominami,S Takemori,T Omura,

For similar cells: cellular structures: intracellular space: cytoplasm: cytoplasmic structures: organelles: mitochondria research abstracts see: cells: cellular structures: intracellular space: cytoplasm: cytoplasmic structures: organelles: mitochondria research

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Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 94

Page Numbers: 1711-4

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Nov

YEAR: 1983

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Keywords Mesh Terms:

KEYWORDS: Mitochondria

MESH TERMS: enzymology

Chemical & Substance for Abstract: Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. Information

Substance Name: Cytochrome P-450 Enzyme System

Registry Number: 9035-51-2

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Country: JAPAN

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MEDLINETA: J Biochem

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