Parathyroid morphology in gerbils after thyroidectomy and calcium administration.

Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Research Abstract Details 

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Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Abstract Text:

L Boquist,B Fåhraeus,

Morphological studies of the parathyroid glands from adult Mongolian gerbils in which hypercalcaemia had been induced by thyroidectomy and calcium injections for 2-19 days were carried out. The potassium pyro-antimonate technique and subsequent X-ray analysis of the precipitates were used for ultrastructural localization of cations. Ultrastructurally, most (suppressed) chief cells exhibited a dense cytoplasm, medium-sized or large mitochondria, glycogen particles, inconspicuous endoplasmic reticulum and Golgi complex, calcium-containing precipitates mainly in mitochondria and nuclei, and sometimes also lysosomal bodies and accumulations of secretory granules which occasionally seemed to be discharged into cytoplasmic vacuoles. A few parenchymal cells showed a low cytoplasmic density, few organelles, and structurally altered mitochondria, occasionally with associated smooth-surfaced vacuoles. These cells possessed calcium-containing precipitates in mitochondria, smooth-surfaced vacuoles, and also diffusely in the cytosol. It is concluded, that, in the main part of the parenchymal cells, the hypercalcaemia had resulted in a suppression primarily of the synthetic and later also of the secretory activity, and that the calcium-containing precipitation is different in the chief cell variants.

Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Publishing Authors By Initials

L Boquist,B Fåhraeus,

For similar surgical procedures, operative: endocrine surgical procedures: thyroidectomy research abstracts see: surgical procedures, operative: endocrine surgical procedures: thyroidectomy research

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Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica et microbiologica Scandinavica. S

VOLUME: 83

Page Numbers: 539-49

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ISSN: 0365-4184

DAY: 20

MONTH: Sep

YEAR: 1975

Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Information

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LANGUAGE: eng

NlmUniqueID: 7508468

Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Keywords Mesh Terms:

KEYWORDS: Thyroidectomy

MESH TERMS: ultrastructure

Chemical & Substance for Abstract: Parathyroid morphology in gerbils after thyroidectomy and calcium administration. Information

Substance Name: Calcium

Registry Number: 7440-70-2

Grant and Affiliation Information for Parathyroid morphology in gerbils after thyroidectomy and calcium administration.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Scand [A

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