Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation.

Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Research Abstract Details 

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Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Abstract Text:

It has been hypothesized that spontaneous panic is distinct from anticipatory anxiety, which activates the hypothalamic-pituitary-adrenal (HPA) axis. Panic attacks characterized by prominent respiratory symptoms, such as those induced by sodium lactate, are not associated with increases in cortisol. We examined blood cortisol responses to CO2-induced panic. Cortisol levels did not increase and actually decreased significantly in 10 panicking subjects with panic disorder. No reductions were noted after 20 min of CO2 inhalation in either eight normal comparison subjects or six non-panicking panic disorder patients. These results lend support to the hypothesis that the pathophysiological mechanism underlying CO2-induced panic is different from that underlying general or anticipatory anxiety.

Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Publishing Authors By Initials

For similar endocrine system: endocrine glands: pituitary-adrenal system research abstracts see: endocrine system: endocrine glands: pituitary-adrenal system research

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Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 86

Page Numbers: 93-8

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 31

MONTH: May

YEAR: 1999

Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Keywords Mesh Terms:

KEYWORDS: Pituitary-Adrenal System

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation. Information

Substance Name: Hydrocortisone

Registry Number: 50-23-7

Grant and Affiliation Information for Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation.

AFFILIATION: Department of Psychiatry, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York 10032, USA.

Country: IRELAND

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MEDLINETA: Psychiatry Res

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