p21-activated kinase signaling in breast cancer.

p21-activated kinase signaling in breast cancer. Research Abstract Details 

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p21-activated kinase signaling in breast cancer. Abstract Text:

Anupama E Gururaj,Suresh K Rayala,Rakesh Kumar,

The p21-activated kinases signal through a number of cellular pathways fundamental to growth, differentiation and apoptosis. A wealth of information has accumulated at an impressive pace in the recent past, both with regard to previously identified targets for p21-activated kinases that regulate the actin cytoskeleton and cellular stress pathways and with regard to newly identified targets and their role in cancer. Emerging data also provide new clues towards a previously unappreciated link between these various cellular processes. The present review attempts to provide a quick tutorial to the reader about the evolving significance of p21-activated kinases and small GTPases in breast cancer, using information from mouse models, tissue culture studies, and human materials.

p21-activated kinase signaling in breast cancer. Publishing Authors By Initials

AE Gururaj,SK Rayala,R Kumar,

For similar enzymes and coenzymes: enzymes: transferases: phosphotransferases: phosphotransferases (alcohol group acceptor): protein kinases: protein-serine-threonine kinases: p21-activated kinases research abstracts see: enzymes and coenzymes: enzymes: transferases: phosphotransferases: phosphotransferases (alcohol group acceptor): protein kinases: protein-serine-threonine kinases: p21-activated kinases research

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p21-activated kinase signaling in breast cancer. Journal Published:

PUBLICATION TYPE: Review

Journal: Breast cancer research : BCR

VOLUME: 7

Page Numbers: 5-12

Journal Abbreviation: Breast Cancer Res.

ISSN: 1465-542X

DAY: 2

MONTH: 11

YEAR: 2004

p21-activated kinase signaling in breast cancer. Information

Number of References: 80

LANGUAGE: eng

NlmUniqueID: 100927353

p21-activated kinase signaling in breast cancer. Keywords Mesh Terms:

KEYWORDS: p21-Activated Kinases

MESH TERMS: metabolism

Chemical & Substance for Abstract: p21-activated kinase signaling in breast cancer. Information

Substance Name: GTP Phosphohydrolases

Registry Number: EC 3.6.1.-

Grant and Affiliation Information for p21-activated kinase signaling in breast cancer.

AFFILIATION: Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. aegururaj@mdanderson.org

Country: England

AGENCY: United States NCI

GRANT: CA90970

ACRONYM: CA

MEDLINETA: Breast Cancer Res

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